Complete assignments of 1h and 13c nmr data for trypanocidal eremantholide c oxide derivatives.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorGuimarães, Dênia Antunes Saúde-
Autor(es): dc.creatorPerry, Katia da Silva Peixoto-
Autor(es): dc.creatorRaslan, Delio Soares-
Autor(es): dc.creatorChiari, Egler-
Autor(es): dc.creatorBarrero, Alejandro Fernández-
Autor(es): dc.creatorOltra, Juan Enrique-
Data de aceite: dc.date.accessioned2025-08-21T15:22:23Z-
Data de disponibilização: dc.date.available2025-08-21T15:22:23Z-
Data de envio: dc.date.issued2017-03-10-
Data de envio: dc.date.issued2017-03-10-
Data de envio: dc.date.issued2007-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/7353-
Fonte completa do material: dc.identifierhttp://onlinelibrary.wiley.com/doi/10.1002/mrc.2093/epdf-
Fonte completa do material: dc.identifierhttps://doi.org/10.1002/mrc.2093-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1012271-
Descrição: dc.descriptionThe chemical transformations of eremantholide C (1), a trypanocidal sesquiterpene lactone isolated from Lychnophora trichocarpha Spreng., gave five new oxide derivatives: 3 -hydroxyeremantholide C (2), 1 -formyleremantholide C (3), 1 -carboxyeremantholide C (4), 1 -carbomethoxyeremantholide C (5) and sodium 1 -carboxylate of eremantholide C (6). The 1H and 13C NMR data of all these derivatives were assigned based on 1D and 2D techniques. The derivatives were evaluated against Y and CL strains of Trypanosoma cruzi. All of them were inactive against the Y strain. Compounds 2 and 5 displayed 100% activity on the CL strain while compounds 4 and 6were partially active on the CL strain. Copyright  2007 John Wiley & Sons, Ltd.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectLychnophora trichocarpha-
Palavras-chave: dc.subjectSesquiterpene lactone-
Título: dc.titleComplete assignments of 1h and 13c nmr data for trypanocidal eremantholide c oxide derivatives.-
Aparece nas coleções:Repositório Institucional - UFOP

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