Antibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorAmparo, Tatiane Roquete-
Autor(es): dc.creatorRodrigues, Ivanildes Vasconcelos-
Autor(es): dc.creatorSeibert, Janaína Brandão-
Autor(es): dc.creatorSouza, Rafaella Hilda Zaniti-
Autor(es): dc.creatorOliveira, Amanda Ribeiro de-
Autor(es): dc.creatorCabral, Vivette Appolinário Rodrigues-
Autor(es): dc.creatorVieira, Paula Melo de Abreu-
Autor(es): dc.creatorBrandão, Geraldo Célio-
Autor(es): dc.creatorOkuma, Adriana Akemi-
Autor(es): dc.creatorVieira Filho, Sidney Augusto-
Autor(es): dc.creatorTeixeira, Luiz Fernando de Medeiros-
Autor(es): dc.creatorSouza, Gustavo Henrique Bianco de-
Data de aceite: dc.date.accessioned2025-08-21T15:16:57Z-
Data de disponibilização: dc.date.available2025-08-21T15:16:57Z-
Data de envio: dc.date.issued2018-05-14-
Data de envio: dc.date.issued2018-05-14-
Data de envio: dc.date.issued2017-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/handle/123456789/9928-
Fonte completa do material: dc.identifierhttps://www.tandfonline.com/doi/abs/10.1080/14786419.2017.1354182?journalCode=gnpl20-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1009085-
Descrição: dc.descriptionThe crude ethanol extract (CEE) and fractions from branches of Protium spruceanum were subjected to antibacterial and cytotoxicity assays. Compounds of the most active fraction were identified by GC-MS and LC-MS. CEE was active against 19 bacteria and the ethyl acetate fraction (EAF) showed the lowest minimum bactericidal concentration (MBC 0.3–80.0 mg/mL). Through time-kill assay was observed that EAF induced rapid bactericidal effect against Staphylococcus saprophyticus. The cytotoxicity tests against L929 fibroblasts showed great potential of EAF on the treatment of infections caused by five bacteria (MBC < IC50). The results provide in vitro scientific support to the possible application of branches of P. spruceanum as antimicrobial agent that may contribute for treatment of infections.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectProtium spruceanum-
Palavras-chave: dc.subjectCytotoxicity-
Palavras-chave: dc.subjectAntbacterial activity-
Título: dc.titleAntibacterial activity of extract and fractions from branches of Protium spruceanum and cytotoxicity on fibroblasts.-
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