High-sugar diet intake, physical activity, and gut microbiota crosstalk : implications for obesity in rats.

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MetadadosDescriçãoIdioma
Autor(es): dc.creatorNeves, Viviano Gomes de Oliveira-
Autor(es): dc.creatorOliveira, Daiane Teixeira de-
Autor(es): dc.creatorOliveira, Deborah Campos-
Autor(es): dc.creatorPerucci, Luiza Oliveira-
Autor(es): dc.creatorSantos, Talita Adriana Pereira dos-
Autor(es): dc.creatorFernandes, Isabela da Costa-
Autor(es): dc.creatorSousa, Graziele Galdino de-
Autor(es): dc.creatorBarboza, Natália Rocha-
Autor(es): dc.creatorCota, Renata Guerra de Sá-
Data de aceite: dc.date.accessioned2025-08-21T15:16:08Z-
Data de disponibilização: dc.date.available2025-08-21T15:16:08Z-
Data de envio: dc.date.issued2021-11-22-
Data de envio: dc.date.issued2021-11-22-
Data de envio: dc.date.issued2019-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/jspui/handle/123456789/14013-
Fonte completa do material: dc.identifierhttps://doi.org/10.1002/fsn3.1842-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1008574-
Descrição: dc.descriptionThis study aims to evaluate the effect of long-term high-sugar diet (HSD) intake and regular physical activity on gut microbiota as well as its health impact. Weaned male Wistar rats were fed with standard chow diet (SSD) or HSD ad libitum and subjected or not to regular swimming training with a workload (2% of body weight) for 15 weeks. Feces samples were used on microbiome analysis using 16S rRNA amplicon sequencing. HSD increased body mass, adipose cushions, and the serum levels of triglycerides and VLDL, also changed the bacteria taxons associated with metabolic disorders (increase taxons belonging to Proteobacteria phylum and decrease Pediococcus genus); the swim training reverted these changes. SSD intake increased the abundance of bacteria associated with metabolization of dietary fiber. Training in association with SSD consumption beneficially modulated the microbiota, increasing the Bacteroidetes, Bacteroidaceae, Porphyromonadaceae, Parabacteroides, and Lactobacillaceae, and decreasing the Firmicute/Bacteroidetes ratio; training was not able to maintain this profile in animals SHD-fed. Physical training modulates the gut microbiota reversing the obesogenic response caused by SHD. However, training itself is not efficient for up-regulating the probiotic bacteria in comparison to its association with a balanced diet.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsaberto-
Direitos: dc.rightsThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. Source: The article PDF.-
Palavras-chave: dc.subjectSwimming training-
Título: dc.titleHigh-sugar diet intake, physical activity, and gut microbiota crosstalk : implications for obesity in rats.-
Aparece nas coleções:Repositório Institucional - UFOP

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