Enhanced mechanical properties, anti-biofilm activity, and cytocompatibility of a methacrylate-based polymer loaded with native multiwalled carbon nanotubes.

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Autor(es): dc.creatorRodrigues, Ricardo Antonio Alpino-
Autor(es): dc.creatorSilva, Rosangela Maria Ferreira da Costa e-
Autor(es): dc.creatorFerreira, Luiza de Almeida Queiroz-
Autor(es): dc.creatorBranco, Natália Tavares Teixeira-
Autor(es): dc.creatorÁvila, Érick de Souza-
Autor(es): dc.creatorPeres, Anderson Maia-
Autor(es): dc.creatorBraga, Weslley Fernandes-
Autor(es): dc.creatorDias, Augusto César Sette-
Autor(es): dc.creatorAndrade, Ângela Leão-
Autor(es): dc.creatorDibb, Regina Guenka Palma-
Autor(es): dc.creatorMagalhães, Cláudia Silami de-
Autor(es): dc.creatorLadeira, Luiz Orlando-
Autor(es): dc.creatorSilveira, Rodrigo Richard da-
Autor(es): dc.creatorMoreira, Allyson Nogueira-
Autor(es): dc.creatorMartins Júnior, Paulo Antônio-
Autor(es): dc.creatorYamauti, Mônica-
Autor(es): dc.creatorDiniz, Ivana Márcia Alves-
Data de aceite: dc.date.accessioned2025-08-21T15:09:47Z-
Data de disponibilização: dc.date.available2025-08-21T15:09:47Z-
Data de envio: dc.date.issued2023-11-16-
Data de envio: dc.date.issued2023-11-16-
Data de envio: dc.date.issued2021-
Fonte completa do material: dc.identifierhttp://www.repositorio.ufop.br/jspui/handle/123456789/17810-
Fonte completa do material: dc.identifierhttps://www.sciencedirect.com/science/article/pii/S1751616122004167-
Fonte completa do material: dc.identifierhttps://doi.org/10.1016/j.jmbbm.2022.105511-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/capes/1003988-
Descrição: dc.descriptionObjectives: We aimed to optimize the mechanical and biological properties of a conventional methacrylate-based dental polymer by loading it with double- and triple-walled carbon nanotubes as growth (DTWCNTG). Methods: A formulation of bisphenol A-glycidyl methacrylate and triethylene glycol dimethacrylate (mass ratio = 2:1) was mixed with DTWCNTG at concentrations of 0.0% (control), 0.001%, 0.005%, and 0.010%. The concentrations were physicochemical and morphologically evaluated, and antibacterial activity was assessed by seeding a Streptococcus mutans strain (ATCC 25175) on the experimental polymeric surfaces. Cellular survival and osteodifferentiation were evaluated in epithelial (HaCat) and preosteoblast cells (MC3T3-E1). Results: The 0.001% DTWCNTG concentration yielded higher compressive strength, elastic modulus, flexural strength, flexural modulus, water sorption, and solubility than the control. The degree of conversion and color did not significantly change with a low amount of DTWCNTG incorporated into the polymer. Antibacterial activity significantly improved when tested on the 0.001% DTWCNTG discs. No groups showed cytotoxicity in a short-term analysis and adding DTWCNTG favored MC3T3-E1 mineralization over the control, particularly in the 0.001% formulation. Significance: The micro-addition of 0.001% DTWCNTG confers mechanical resistance, antimicrobial properties, and bioactivity to methacrylate-based polymers without significantly compromising color. Incorporating DTWCNTG improved dental composite properties and could be a biomodified material for minimally invasive procedures.-
Formato: dc.formatapplication/pdf-
Idioma: dc.languageen-
Direitos: dc.rightsrestrito-
Palavras-chave: dc.subjectMultiwalled carbon nanotubes-
Palavras-chave: dc.subjectMethacrylate-based polymers-
Palavras-chave: dc.subjectDental resin composites-
Palavras-chave: dc.subjectAntibacterial activity-
Palavras-chave: dc.subjectBiomodification-
Título: dc.titleEnhanced mechanical properties, anti-biofilm activity, and cytocompatibility of a methacrylate-based polymer loaded with native multiwalled carbon nanotubes.-
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