Experimental kinetics of infection induced by Yersinia pseudotuberculosis isolated from stock animals

Registro completo de metadados
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorMartins, Carlos Henrique Gomes-
Autor(es): dc.creatorFalcão, Deise Pasetto-
Data de aceite: dc.date.accessioned2021-03-10T16:46:51Z-
Data de disponibilização: dc.date.available2021-03-10T16:46:51Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2004-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/S0074-02762004000600015-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/7945-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/7945-
Descrição: dc.descriptionThe course of in vivo infection of five isolates of Yersinia pseudotuberculosis was followed for three weeks in Swiss mice. The strains were isolated from diarrheic and normal feces and mesenteric lymph nodes of healthy and sick stock animals. Four strains of serogroup O:3 and one of serogroup O:1a, with and without the virulence plasmid, were inoculated intragastrically and intravenously in the mice. Groups of five animals were sacrificed at 6 h and 3, 6, 10, 15, and 21 days after inoculation, and organs and tissues were checked for possible macroscopic alterations. Development of infection was monitored at these times by performing viable bacterial counts in homogenates of selected tissues. The animals were cheked daily for clinical alterations. The results of the study showed that strains with the virulence plasmid infected organs and tissues at various times and at varying intensity by both routes of infection, the strain of type O:1a being the most invasive. Moreover, clinical and pathological alterations occurred only in animals inoculated with bacteria carrying the virulence plasmid, regardless of the route of infection.-
Formato: dc.format621-626-
Idioma: dc.languageen-
Publicador: dc.publisherInstituto Oswaldo Cruz, Ministério da Saúde-
Relação: dc.relationMemórias do Instituto Oswaldo Cruz-
Relação: dc.relation2.833-
Relação: dc.relation1,172-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectYersinia pseudotuberculosis-
Palavras-chave: dc.subjectkinetics of infection-
Palavras-chave: dc.subjectvirulence-
Título: dc.titleExperimental kinetics of infection induced by Yersinia pseudotuberculosis isolated from stock animals-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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