No relationship found between point heteroplasmy in mitochondrial DNA control region and age range, sex and haplogroup in human hairs

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorde Camargo, Maria Angelica-
Autor(es): dc.creatorPaneto, Greiciane G.-
Autor(es): dc.creatorde Mello, Aline C. O.-
Autor(es): dc.creatorMartins, Joyce A.-
Autor(es): dc.creatorBarcellos, William-
Autor(es): dc.creatorCicarelli, Regina Maria Barretto-
Data de aceite: dc.date.accessioned2021-03-10T16:46:44Z-
Data de disponibilização: dc.date.available2021-03-10T16:46:44Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2011-02-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s11033-010-0220-1-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/7893-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/7893-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionProcesso FAPESP: 05/03984-5-
Descrição: dc.descriptionProcesso FAPESP: 07/05647-1-
Descrição: dc.descriptionCNPq: 2007-0/140052-
Descrição: dc.descriptionThe analysis of heteroplasmy (presence of more than one type of mitochondrial DNA in an individual) is used as a tool in human identification studies, anthropology, and most currently in studies that relate heteroplasmy with longevity. The frequency of heteroplasmy and its correlation with age has been analyzed using different tissues such as blood, muscle, heart, bone and brain and in different regions of mitochondrial DNA, but this analysis had never been performed using hair samples. In this study, samples of hair were sequenced in order to ascertain whether the presence or not of heteroplasmy varied according to age, sex and origin of haplogroup individuals. The samples were grouped by age (3 groups), gender (male and female) and haplogroup of origin (European, African and Native American), and analyzed using the chi-square statistical test (chi(2)). Based in statistical results obtained, we conclude that there is no relationship between heteroplasmy and sex, age and haplogroup origin using hair samples.-
Formato: dc.format1219-1223-
Idioma: dc.languageen-
Publicador: dc.publisherSpringer-
Relação: dc.relationMolecular Biology Reports-
Relação: dc.relation1.889-
Relação: dc.relation0,721-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectHeteroplasmy-
Palavras-chave: dc.subjectMitochondrial DNA-
Palavras-chave: dc.subjectHair-
Palavras-chave: dc.subjectAge-
Palavras-chave: dc.subjectSex-
Palavras-chave: dc.subjectHaplogroup-
Título: dc.titleNo relationship found between point heteroplasmy in mitochondrial DNA control region and age range, sex and haplogroup in human hairs-
Tipo de arquivo: dc.typelivro digital-
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