The zymogen-enteropeptidase system: A practical approach to study the regulation of enzyme activity by proteolytic cleavage

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorPizauro, J. M.-
Autor(es): dc.creatorFerro, J. A.-
Autor(es): dc.creatorde Lima, ACF-
Autor(es): dc.creatorRoutman, K. S.-
Autor(es): dc.creatorPortella, M. C.-
Data de aceite: dc.date.accessioned2021-03-10T16:38:21Z-
Data de disponibilização: dc.date.available2021-03-10T16:38:21Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2004-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/bmb.2004.494032010311-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/3926-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/3926-
Descrição: dc.descriptionThe present research describes an efficient procedure to obtain high levels of trypsinogen and chymotrypsinogen by using a simple, rapid, and easily reproducible method. The extraction process and the time-course of activation of zymogens can be carried out in a single laboratory period, without sophisticated equipment. The main objective was to prepare a laboratory class that would stimulate student interest in enzyme regulation, exploring the fact that the catalytic activity of some enzymes is regulated by different mechanisms. The regulation of proteolytic enzymes requires the synthesis of an inactive zymogen and its being irreversibly switched on by specific proteolytic cleavage.-
Formato: dc.format45-48-
Idioma: dc.languageen-
Publicador: dc.publisherAmer Soc Biochemistry Molecular Biology Inc-
Relação: dc.relationBiochemistry and Molecular Biology Education-
Relação: dc.relation1.036-
Relação: dc.relation0,370-
Direitos: dc.rightsopenAccess-
Palavras-chave: dc.subjectzymogen-
Palavras-chave: dc.subjecttrypsin-
Palavras-chave: dc.subjectchymotrypsin-
Palavras-chave: dc.subjectenteropeptidase-
Palavras-chave: dc.subjectenzyme regulation-
Palavras-chave: dc.subjectproteolytic cleavage-
Título: dc.titleThe zymogen-enteropeptidase system: A practical approach to study the regulation of enzyme activity by proteolytic cleavage-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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