Biocompatibility, bioactivity, porosity, and sealer/dentin interface of bioceramic ready-to-use sealers using a dentin-tube model

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCentro Universitário Sagrado Coracao (UNISAGRADO)-
Autor(es): dc.creatorInada, Rafaela Nanami Handa-
Autor(es): dc.creatorSilva, Evelin Carine Alves-
Autor(es): dc.creatorLopes, Camila Soares-
Autor(es): dc.creatorQueiroz, Marcela Borsatto-
Autor(es): dc.creatorTorres, Fernanda Ferrari Esteves-
Autor(es): dc.creatorda Silva, Guilherme Ferreira-
Autor(es): dc.creatorCerri, Paulo Sérgio-
Autor(es): dc.creatorGuerreiro–Tanomaru, Juliane Maria-
Autor(es): dc.creatorTanomaru-Filho, Mário-
Data de aceite: dc.date.accessioned2025-08-21T22:26:35Z-
Data de disponibilização: dc.date.available2025-08-21T22:26:35Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-024-66616-7-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/309766-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/309766-
Descrição: dc.descriptionThis study evaluated the biocompatibility, bioactivity, porosity, and sealer/dentin interface of Sealer Plus BC (SP), Bio-C Sealer (BIOC), TotalFill BC Sealer (TF), and AH Plus (AHP). Dentin tubes filled with the sealers and empty tubes (control group) were implanted in the subcutaneous tissue of rats for different periods (n = 6 per group/period). Number of inflammatory cells (ICs), capsule thickness, von Kossa reaction, interleukin-6 (IL-6) and osteocalcin (OCN) were evaluated. Porosity and voids in the interface dentin/sealers were assessed by micro-computed tomography. The data were submitted to ANOVA/Tukey’s tests (α = 0.05). Greater capsule thickness, ICs and IL-6 immunolabeling cells were observed in AHP. No significant difference in thickness of capsule, ICs, and IL-6- immunolabeling cells was detected between SP and TF, in all periods, and after 30 and 60 days between all groups. At 60 days all groups had reduction in capsule thickness, ICs and IL-6 immunolabeling cells. Von Kossa-positive and birefringent structures were observed in the capsules around the sealers. BIOC, SP, and TF exhibited OCN-immunolabeling cells. All sealers had porosity values below 5%, besides low and similar interface voids. BIOC, SP and TF are biocompatible, bioactive, and have low porosity and voids. The dentin-tube model used is an alternative for evaluating bioceramic materials.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionSchool of Dentistry Department of Restorative Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Dentistry Centro Universitário Sagrado Coracao (UNISAGRADO)-
Descrição: dc.descriptionLaboratory of Histology and Embryology Department of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionSchool of Dentistry Department of Restorative Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionLaboratory of Histology and Embryology Department of Morphology Genetics Orthodontics and Pediatric Dentistry School of Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 2017/14305-9-
Descrição: dc.descriptionFAPESP: 2017/19049-0-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleBiocompatibility, bioactivity, porosity, and sealer/dentin interface of bioceramic ready-to-use sealers using a dentin-tube model-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.