Synthesis of a Bioactive Nitric Oxide-Releasing Polymer from S-Nitrosated Starch

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorFederal Technological University of Paraná (UTFPR)-
Autor(es): dc.contributorUniversidade Estadual de Maringá (UEM)-
Autor(es): dc.contributorFederal Technological University of Paraná-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorda Silva, Jéssica Fernanda-
Autor(es): dc.creatorde Almeida, Edson Araujo-
Autor(es): dc.creatorKaroleski, Geovana Ellen-
Autor(es): dc.creatorKoloshe, Everton-
Autor(es): dc.creatorPeron, Ana Paula-
Autor(es): dc.creatorJob, Aldo Eloizo-
Autor(es): dc.creatorLeimann, Fernanda Vitória-
Autor(es): dc.creatorShirai, Marianne Ayumi-
Autor(es): dc.creatorda Silva Gonzalez, Regiane-
Data de aceite: dc.date.accessioned2025-08-21T20:04:49Z-
Data de disponibilização: dc.date.available2025-08-21T20:04:49Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-10-08-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1021/acsomega.4c03255-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/309696-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/309696-
Descrição: dc.descriptionThe incorporation of nitric oxide (NO) into polymeric matrices minimizes degradation and facilitates controlled release. This optimization increases the field of application of NO, in dressings, food protective films, and implant devices, among others. This work presents an economical and easy way to manufacture bioactive nitric oxide-releasing polymer (BioNOR-P) and evaluates its bactericidal and antioxidant activity (AA), mechanical behavior, cytotoxicity, and genotoxicity, seeking future use in different applications. The BioNOR-P film was obtained by a casting method, forming a homogeneous, transparent film with good mechanical properties. The release of NO in an aqueous medium showed the film’s ability to release NO slowly, at a rate of 0.58 nmol/g-1 min-1. Furthermore, the noncytotoxicity and antioxidant activity observed by NO release from BioNOR-P, as well as the ability to inhibit bacterial growth, may aid in the development of a NO-released polymer with different areas of application.-
Descrição: dc.descriptionFederal Technological University of Paraná (UTFPR), Campo Mourão Campus-
Descrição: dc.descriptionPost-Graduation Program of Chemistry State University of Maringá (UEM), Paraná-
Descrição: dc.descriptionFederal Technological University of Paraná, Paraná-
Descrição: dc.descriptionDepartment of Biodiversity and Nature Conservation Federal Technological University of Paraná, Paraná-
Descrição: dc.descriptionDepartment of Physics State University Paulista “Julio de Mesquita Filho”, Campus, São Paulo-
Descrição: dc.descriptionPostgraduate Program in Food Technology Federal Technological University of Paraná, Paraná-
Descrição: dc.descriptionDepartment of Chemistry Federal Technological University of Paraná, Paraná-
Descrição: dc.descriptionDepartment of Physics State University Paulista “Julio de Mesquita Filho”, Campus, São Paulo-
Formato: dc.format41268-41278-
Idioma: dc.languageen-
Relação: dc.relationACS Omega-
???dc.source???: dc.sourceScopus-
Título: dc.titleSynthesis of a Bioactive Nitric Oxide-Releasing Polymer from S-Nitrosated Starch-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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