Inflammatory Bowel Disease Associated with Lymphangiectasia in a Dachshund Dog

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorCentro Universitário de Lavras (UNILAVRAS)-
Autor(es): dc.contributorUniversidade Federal de Lavras (UFLA)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorResende, Isa Lúcia Sousa-
Autor(es): dc.creatorBastos, Karolyne Oliveira-
Autor(es): dc.creatorRibeiro, Diego-
Autor(es): dc.creatorFerreira, Walter Araújo-
Autor(es): dc.creatorRibeiro, Catarina Brenha-
Autor(es): dc.creatorDe Souza Pereira, Lucas-
Autor(es): dc.creatorMuzzi, Ruthnéa Aparecida Lázaro-
Autor(es): dc.creatorDe Abreu, Claudine Botelho-
Data de aceite: dc.date.accessioned2025-08-21T18:53:35Z-
Data de disponibilização: dc.date.available2025-08-21T18:53:35Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.22456/1679-9216.134517-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/309580-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/309580-
Descrição: dc.descriptionBackground: Inflammatory bowel disease (IBD) is a chronic enteropathy that causes gastrointestinal disorders in dogs and cats. It can result in protein loss generally, IBD can result in protein loss when a lymphoplasmacytic enteritis type is envolved. In this case, it is frequently associated with lymphangiectasia. Clinical signs include diarrhea, vomiting and progressive weight loss. This disease mainly affects middle-aged animals. There is only one report in young dog and no reports were observed in Dachshund breed. The objective of this article is reporting the association of inflammatory bowel disease and lymphangiectasia in a young female dachshund dog. Case: It was attended a 2-year-old female Dachshund dog, weighing 7.5 kg. The animal presented with a history of diarrhea, vomiting, weight loss and hyporexia. In the physical examination, it was detected prolonged capillary refill time (longer than two seconds), dehydration of 5 to 6%, muffled pulmonary auscultation on both sides of the thorax (suggesting pleural effusion), abdominal pain, flatulence and a positive balloon test (suggesting ascites). Thoracocentesis and abdominocentesis were performed to drain the pleural effusion and ascites, respectively. Both fluids were classified as transudate. The blood count resulted in normocytic normochromic anemia, neutrophilic leukocytosis, eosinopenia, lymphopenia, monocytosis and thrombocytosis. Serum biochemistry findings included hyponatremia, hypochloremia, hypocalcemia, hypocholesterolemia, hypoproteinemia, hypoalbuminemia, hypoglobulinemia and increased alkaline phosphatase. Abdominal ultrasonography showed thickening of the duodenal wall, some segments with hyperechogenic streaks in the jejunal mucosa, colon with increased parietal thickness and presence of free peritoneal fluid. The histopathological analysis of intestinal and gastric fragments, obtained by surgical biopsy, confirmed the diagnosis of lymphoplasmacytic IBD associated with lymphangiectasia. It was classified as severe according to the canine inflammatory bowel disease activity index (CIBDAI). The patient was admitted to hospital and submitted to dietary management, immunosuppressants, antibiotics and supportive therapy. However, the dog has died after 10 weeks. Discussion: The prognosis of IBD is highly variable, depends on therapeutic response and extent of intestinal damage. Dietary therapy associated with anti-inflammatories and immunosuppressants may result in IBD remission. This is characterized by periods of improvement that can last from months to years. Although, in more severe cases, some animals do not respond adequately and relapsed. Lymphangiectasia is a common complication of IBD in dogs, resulting in lymph extravasation and protein loss into the intestinal lumen. Those patients may develop protein-calorie depletion, disabling strokes, or intractable diarrhea. Hypoalbuminemia is an unfavorable prognostic marker. Firstly, in this case, the CIBDAI score was severe (14 points). Along treatment, it evolved into a clinically insignificant condition (2 points). However, later, there was regression to clinically severe disease (12 points). The dog did not respond adequately to the therapy, despite the indicated treatment have been instituted. It had continuously effusions, diarrhea and progressed to cachexia. Hypoproteinemia probably contributed to the severity of the clinical condition and therapeutic response failure, resulting in the animal's death at 10 weeks from the first appointment.-
Descrição: dc.descriptionCentro Universitário de Lavras (UNILAVRAS), MG-
Descrição: dc.descriptionUniversidade Federal de Lavras (UFLA)-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP), SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP), SP-
Idioma: dc.languagept_BR-
Relação: dc.relationActa Scientiae Veterinariae-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCIBDAI-
Palavras-chave: dc.subjectdiarrhea-
Palavras-chave: dc.subjectgastrointestinal-
Palavras-chave: dc.subjecthypoproteinemia-
Palavras-chave: dc.subjectinflammation-
Palavras-chave: dc.subjectlymphangiectasis-
Palavras-chave: dc.subjectlymphatic system-
Título: dc.titleInflammatory Bowel Disease Associated with Lymphangiectasia in a Dachshund Dog-
Título: dc.titleDoença intestinal inflamatória associada com linfangiectasia em um cão Dachshund-
Tipo de arquivo: dc.typelivro digital-
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