Oral/Perioral Reactions to Injectable Soft Tissue Fillers: A Clinicopathological Multicentric Study

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorEstácio de Sá University-
Autor(es): dc.contributorFederal University of Rio de Janeiro-
Autor(es): dc.contributorUniversidade Federal de Pernambuco (UFPE)-
Autor(es): dc.contributorFederal University of Paraíba-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAC Camargo Cancer Center-
Autor(es): dc.contributorState University of Montes Claros-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorHospital General Dr. Manuel Gea González-
Autor(es): dc.contributorUniversity of the Basque Country-
Autor(es): dc.contributorPrivate Practice-
Autor(es): dc.contributorMetropolitan Autonomous University Xochimilco-
Autor(es): dc.creatorPires, Fábio Ramoa-
Autor(es): dc.creatorSaid, Aurélio Marcos Tsutyia-
Autor(es): dc.creatorNetto, Juliana de Noronha Santos-
Autor(es): dc.creatorda Cruz Perez, Danyel Elias-
Autor(es): dc.creatorBonan, Paulo Rogério Ferreti-
Autor(es): dc.creatorMartins, Helder Domiciano Dantas-
Autor(es): dc.creatorKaminagakura, Estela-
Autor(es): dc.creatorAlves, Fábio de Abreu-
Autor(es): dc.creatorMartelli Júnior, Hercílio-
Autor(es): dc.creatorMachado, Renato Assis-
Autor(es): dc.creatorLopes, Márcio Ajudarte-
Autor(es): dc.creatorSantos-Silva, Alan Roger-
Autor(es): dc.creatorVargas, Pablo Agustin-
Autor(es): dc.creatorLouredo, Brendo Vinicius Rodrigues-
Autor(es): dc.creatorVega-Memije, María Elisa-
Autor(es): dc.creatorCano-Aguilar, Luis Enrique-
Autor(es): dc.creatorToussaint-Caire, Sonia-
Autor(es): dc.creatorMonteiro, Mariene da Silva-
Autor(es): dc.creatorFonseca, Thamyres Campos-
Autor(es): dc.creatorRomañach, Mário José-
Autor(es): dc.creatorAbrahão, Aline Correa-
Autor(es): dc.creatorAguirre-Urizar, José Manuel-
Autor(es): dc.creatorLafuente Ibáñez-de-Mendoza, Irene-
Autor(es): dc.creatorOlmedo-Campos, Mireya-
Autor(es): dc.creatorMosqueda-Taylor, Adalberto-
Data de aceite: dc.date.accessioned2025-08-21T19:03:01Z-
Data de disponibilização: dc.date.available2025-08-21T19:03:01Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1111/odi.15143-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/309294-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/309294-
Descrição: dc.descriptionObjective: To analyze the characteristics of a series of oral reactions to injectable soft tissue fillers. Materials and Methods: Cases diagnosed as oral reactions to injectable soft tissue fillers were selected from eight Pathology laboratories. Information was retrieved from the laboratory charts and from the review of the hematoxylin and eosin-stained histological slides. Results: The 151 patients showed a mean age of 54.9 years, and 136 (90.1%) were females. Mean time of onset was 20.4 months, and the lips were the most frequent location (72.8%). Most cases presented as asymptomatic isolated nodules, with a mean size of 17.4 mm. Silicone (38.5%), polymethylmetacrylate (33%), and hyaluronic acid (11.9%) were the three most common fillers. Granulomas, foamy macrophages, and multinucleated giant cells were observed in 44%, 51.5%, and 65.3% of the cases, respectively. Time of onset was shorter for males (p = 0.033), and symptoms were common in the upper lip, buccal mucosa, and lower vestibule (p = 0.010). Foamy macrophages were more common in association with silicone and collagen (p < 0.001), whereas multinucleated giant cells were more common in association with polymethylmetacrylate, hydroxiapatite, and polylactic acid (p = 0.012). Conclusion: Clinicians should consider reactions to injectable soft tissue fillers when evaluating asymptomatic submucosal nodules affecting the lips of adult/older females.-
Descrição: dc.descriptionOral Pathology School of Dentistry Rio de Janeiro State University and Post Graduation Program in Dentistry Estácio de Sá University-
Descrição: dc.descriptionPost Graduation Program in Dentistry Estácio de Sá University-
Descrição: dc.descriptionStomatology Department of Oral Diagnosis and Pathology School of Dentistry Federal University of Rio de Janeiro-
Descrição: dc.descriptionOral Pathology Unit School of Dentistry Federal University of Pernambuco-
Descrição: dc.descriptionDepartment of Clinics and Social Dentistry Federal University of Paraíba-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis São Paulo State University-
Descrição: dc.descriptionStomatology AC Camargo Cancer Center-
Descrição: dc.descriptionStomatology Clinic Dental School State University of Montes Claros-
Descrição: dc.descriptionGraduate Program in Oral Biology Piracicaba Dental School State University of Campinas-
Descrição: dc.descriptionSemiology Piracicaba Dental School State University of Campinas-
Descrição: dc.descriptionOral Pathology Piracicaba Dental School State University of Campinas-
Descrição: dc.descriptionDermatology Department Hospital General Dr. Manuel Gea González-
Descrição: dc.descriptionDermatopathology Dermatology Department Hospital General Dr. Manuel Gea González-
Descrição: dc.descriptionOral Pathology Department of Oral Diagnosis and Pathology School of Dentistry Federal University of Rio de Janeiro-
Descrição: dc.descriptionOral Pathology and Medicine Department of Stomatology University of the Basque Country-
Descrição: dc.descriptionPrivate Practice-
Descrição: dc.descriptionHealth Care Department Metropolitan Autonomous University Xochimilco-
Descrição: dc.descriptionDepartment of Bioscience and Oral Diagnosis São Paulo State University-
Idioma: dc.languageen-
Relação: dc.relationOral Diseases-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectfilling-
Palavras-chave: dc.subjecthyaluronic acid-
Palavras-chave: dc.subjectlips-
Palavras-chave: dc.subjectpolymethylmetacrylate-
Palavras-chave: dc.subjectreactions-
Palavras-chave: dc.subjectsilicone-
Título: dc.titleOral/Perioral Reactions to Injectable Soft Tissue Fillers: A Clinicopathological Multicentric Study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.