Indole Derivatives as Promising Anti-Dengue Agents: A Review of Recent Advances

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.creatorJanuário, Marcelo Augusto Pereira-
Autor(es): dc.creatorJunior, Celso de Oliveira Rezende-
Autor(es): dc.creatorCastro-Gamboa, Ian-
Data de aceite: dc.date.accessioned2025-08-21T19:46:46Z-
Data de disponibilização: dc.date.available2025-08-21T19:46:46Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/cbdv.202402517-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/308503-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/308503-
Descrição: dc.descriptionDengue, a mosquito-borne disease transmitted by Aedes mosquitoes, is a significant global health concern. Despite extensive research, effective treatments remain limited. The indole nucleus, known for its diverse pharmacological properties, has emerged as a promising scaffold for anti-dengue drug discovery. This review comprehensively examines recent advancements in the fields of natural products, medicinal chemistry, and computer-aided drug design focused on discovering indole-based anti-dengue agents. We discuss the rationale for targeting indole frameworks, highlight key structural features associated with anti-dengue activity, and summarize recent research findings. The review aims to provide valuable insights for researchers working on developing novel anti-dengue therapeutics.-
Descrição: dc.descriptionDepartament of Biochemistry and Organic Chemistry São Paulo State University–UNESP-
Descrição: dc.descriptionOrganic Chemistry Nucleus Institute of Chemistry Federal University of Uberlândia–UFU-
Descrição: dc.descriptionDepartament of Biochemistry and Organic Chemistry São Paulo State University–UNESP-
Idioma: dc.languageen-
Relação: dc.relationChemistry and Biodiversity-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectchemistry of natural products | computer-aided drug design | indole | organic and medicinal chemistry-
Título: dc.titleIndole Derivatives as Promising Anti-Dengue Agents: A Review of Recent Advances-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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