Can bioelectrical stimulation favor orthodontic treatment? A randomized clinical trial to evaluate tooth movement, patient-centered, and inflammatory biomarker outcomes

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversity Center of the Hermínio Ometto Foundation-
Autor(es): dc.contributorUniversity of Kentucky-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Maryland-
Autor(es): dc.creatorBarsi, Paula Caroline-
Autor(es): dc.creatorSantamaria, Mauro Pedrine-
Autor(es): dc.creatorCasarin, Renato Corrêa Viana-
Autor(es): dc.creatorStolf, Camila Schmidt-
Autor(es): dc.creatorVedovello, Sílvia Amélia Scudeler-
Autor(es): dc.creatorZuppardo, Marcelo Lelis-
Autor(es): dc.creatorBautista, Cristhian Reynaldo Gomez-
Autor(es): dc.creatorZaniboni, Ewerton-
Autor(es): dc.creatorMathias-Santamaria, Ingrid Fernandes-
Autor(es): dc.creatorSantamaria-Jr, Milton-
Data de aceite: dc.date.accessioned2025-08-21T20:09:07Z-
Data de disponibilização: dc.date.available2025-08-21T20:09:07Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.xaor.2023.09.004-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/308375-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/308375-
Descrição: dc.descriptionExogenous bioelectrical stimulation (BES) modulates the bone remodeling. This study aimed to evaluate the effect of BES on clinical, patient-centered, and inflammatory biomarker outcomes of orthodontic tooth movement (OTM). A randomized clinical trial (n = 28) matched for sex (8 men and 6 women in each group) were divided into the control group with a sham device (ie, mouthpiece turned off): OTM + SHAM (mean age of 19.4 years), and the test group: OTM + BES (mean age of 20.1 years). Orthodontic alignment was performed with 0.012-in, 0.014-in, and 0.016-in nickel-titanium wires. BES (10 μA/5 min) was applied immediately after each wire installation, after 48 hours, and once a week until the next wire. The canine-to-canine crowding and little dental irregularity index in the mandibular arch were analyzed. Pain perception was measured at 0, 24, 48, and 72 hours after replacement of the 0.014-in and 0.016-in wires. Inflammatory biomarkers were assessed 48 hours after the replacement of the 0.014-inch wire in gingival fluid. The crowding difference was greater in the OTM + BES than in the OTM + SHAM after 2- and 3-month evaluations and the little index was lower in OTM + BES after 3 months of treatment. During the 0.014-in wire alignment, patient pain perception was lower in the OTM + BES than in the OTM + SHAM at 24 and 48 hours, and lower after 24 hours in the 0.016-in wire alignment. BES treatment increased IL-6 and decreased IL-10 levels in gingival fluid after 48 hours of dental alignment. Exogenous bioelectrical stimulation can accelerate initial OTM, decrease patient pain perception, and modulate inflammatory biomarkers.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionGraduate Program in Orthodontics University Center of the Hermínio Ometto Foundation, São Paulo-
Descrição: dc.descriptionCenter for Oral Health Research College of Dentistry University of Kentucky-
Descrição: dc.descriptionDepartment of Periodontics and Prosthodontics College of Dentistry University of Campinas, São Paulo-
Descrição: dc.descriptionDepartment of Periodontology College of Denistry Institute of Science and Technology São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of General Denistry University of Maryland-
Descrição: dc.descriptionDepartment of Social and Pediatric Dentistry College of Denistry Institute of Science and Technology São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of Periodontology College of Denistry Institute of Science and Technology São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of Social and Pediatric Dentistry College of Denistry Institute of Science and Technology São Paulo State University, São Paulo-
Descrição: dc.descriptionCNPq: 304269/2019-0-
Formato: dc.format464-472-
Idioma: dc.languageen-
Relação: dc.relationAJO-DO Clinical Companion-
???dc.source???: dc.sourceScopus-
Título: dc.titleCan bioelectrical stimulation favor orthodontic treatment? A randomized clinical trial to evaluate tooth movement, patient-centered, and inflammatory biomarker outcomes-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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