Effect of nanometric β-calcium glycerophosphate supplementation in conventional toothpaste on enamel demineralization: An in vitro study

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorFederal University of Rio Grande (FURG)-
Autor(es): dc.contributorUniversidade Federal de Pernambuco (UFPE)-
Autor(es): dc.contributorFederal University of Alfenas (UNIFAL)-
Autor(es): dc.contributorUniversity of Ribeirão Preto - UNAERP-
Autor(es): dc.creatorEmerenciano, Nayara Gonçalves-
Autor(es): dc.creatorDelbem, Alberto Carlos Botazzo-
Autor(es): dc.creatorGonçalves, Francyenne Maira Castro-
Autor(es): dc.creatorde Camargo, Emerson Rodrigues-
Autor(es): dc.creatorde Souza Neto, Francisco Nunes-
Autor(es): dc.creatorGorup, Luiz Fernando-
Autor(es): dc.creatorSilva-Sousa, Yara Teresinha Corrêa-
Autor(es): dc.creatorDanelon, Marcelle-
Data de aceite: dc.date.accessioned2025-08-21T17:50:53Z-
Data de disponibilização: dc.date.available2025-08-21T17:50:53Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jmbbm.2023.106354-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/308064-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/308064-
Descrição: dc.descriptionThe aim of this study was to evaluate the effects of supplementing toothpastes containing 1100 ppm F with micrometric or nanometric [beta]-calcium glycerophosphate (β-CaGPm/β-CaGPn) on artificial enamel demineralization, using a pH cycling model. Bovine enamel blocks (4 mm × 4 mm, n = 120) selected using initial surface hardness were randomly allocated to ten toothpaste groups (n = 12): without fluoride or β-CaGPm or β-CaGPn (Negative control), 1100 ppm F (1100 F), and 1100 ppm F plus 0.125%, 0.25%, 0.5%, and 1.0% of β-CaGPm or β-CaGPn. Blocks were treated two times per day with toothpaste slurry and subjected to five pH cycles (demineralizing and remineralizing solutions) at 37 °C. The final surface hardness, percentage of surface hardness loss (%SH), cross-sectional hardness (ΔKHN), and profile analysis and lesion depth subsurface were analysed using polarized light microscopy (PLM). Fluoride (F), calcium (Ca), and phosphorus (P) concentrations were also measured. Data were analysed using ANOVA and Student-Newman-Keuls tests ([alpha] = 0.001). Blocks treated with 1100 F toothpaste containing 0.5%β-CaGPm or 0.25%β-CaGPn showed with reduced %SH values when compared with those treated with 1100 F alone (p < 0.001). Reduced lesion depths (ΔKHN and PLM) were observed for the slurry made up of 1100 F and 0.25%β-CaGPn (p < 0.001). The addition of β-CaGPm and β-CaGPn did not influence the enamel F concentration, with the 1100 F/0.25%β-CaGPn group exhibiting the highest Ca and P enamel concentrations (p < 0.001). Based on the findings of this in vitro study, we can conclude that the fluoride toothpaste produced a superior effect when combined at an appropriate β-CaGP molar ratio. This effect was achieved with a lower proportion of β-CaGP in the form of nanometric particles.-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry, Rua José Bonifácio 1193, SP-
Descrição: dc.descriptionLIEC-Department of Chemistry Federal University of São Carlos (UFSCar), São Carlos/São Paulo-
Descrição: dc.descriptionSchool of Chemistry and Food Science Federal University of Rio Grande (FURG), Av. Italia km 8, RS-
Descrição: dc.descriptionMaterials Engineering Campus Porto Federal University of Pelotas (UFPel), RS-
Descrição: dc.descriptionInstitute of Chemistry Federal University of Alfenas (UNIFAL), MG-
Descrição: dc.descriptionSchool of Dentistry University of Ribeirão Preto - UNAERP, Ribeirão Preto, SP-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Dentistry-
Idioma: dc.languageen-
Relação: dc.relationJournal of the Mechanical Behavior of Biomedical Materials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDemineralization-
Palavras-chave: dc.subjectDental enamel-
Palavras-chave: dc.subjectFluoride-
Palavras-chave: dc.subjectPhosphate-
Título: dc.titleEffect of nanometric β-calcium glycerophosphate supplementation in conventional toothpaste on enamel demineralization: An in vitro study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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