Vascular hamartoma in horse limbs: presentation, diagnosis, and treatment of two case studies

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Estadual de Londrina (UEL)-
Autor(es): dc.contributorUniversidade Federal de Santa Catarina (UFSC)-
Autor(es): dc.creatorApolonio, Emanuel Vitor Pereira-
Autor(es): dc.creatorGobbo, Laís Loiola-
Autor(es): dc.creatorWoiblet, Nathalia Gouveia-
Autor(es): dc.creatorDinau, Fernando Carmona-
Autor(es): dc.creatorPyles, Mateus Siqueira-
Autor(es): dc.creatorFerrari, Lorena Cardozo-
Autor(es): dc.creatorde Moura Alonso, Juliana-
Autor(es): dc.creatorAlves, Ana Liz Garcia-
Data de aceite: dc.date.accessioned2025-08-21T21:42:51Z-
Data de disponibilização: dc.date.available2025-08-21T21:42:51Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s11259-024-10601-y-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/307926-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/307926-
Descrição: dc.descriptionVascular hamartoma is an abnormal development of endothelial tissue that rarely affects horses. Histopathological examination remains the gold standard for definitive diagnosis, yet the presence of abnormal vascular structures must be carefully differentiated from other vascular anomalies and neoplasms. This report describes two cases of vascular proliferation affecting the skin on the lateral side over the left tarsus and the dorsolateral region over the fetlock joint of two fillies. The clinical history, presentation, and radiographic and sonographic findings in both patients suggested a neoplasm of unknown origin. Surgical excision of the mass was successfully performed in both patients. In one patient, a second surgery was performed six months after the first surgery because of the recurrence of the mass. Histopathological examination revealed a disorganized proliferation of well-differentiated, tortuous, and varied-sized blood vessels hemmed in myxoid tissue with abundant fibrocollagenous bands. Immunohistochemical examination of the endothelium markers factor VIII and ERG revealed positive staining of the mass samples in both cases, confirming their vascular origin. The combination of these markers was effective, providing a reliable option for differentiating vascular proliferation in horses. To the best of the author’s knowledge, this is the first report applying the ERG endothelial marker to horse vascular malformations.-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction São Paulo State University - UNESP-
Descrição: dc.descriptionDepartment of Preventive Veterinary Medicine Londrina State University – UEL, Paraná-
Descrição: dc.descriptionVeterinary Clinic School of Federal University of Santa Catarina – UFSC, Santa Catarina-
Descrição: dc.descriptionDepartment of Veterinary Surgery and Animal Reproduction São Paulo State University - UNESP-
Idioma: dc.languageen-
Relação: dc.relationVeterinary Research Communications-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectEquine surgery-
Palavras-chave: dc.subjectERG-
Palavras-chave: dc.subjectFactor VIII-
Palavras-chave: dc.subjectImmunohistochemistry-
Título: dc.titleVascular hamartoma in horse limbs: presentation, diagnosis, and treatment of two case studies-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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