Characterization of clock proteins in the substantia nigra and subthalamic nucleus of the Sapajus apella primate

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Autor(es): dc.contributorUniversidade de Marília (UNIMAR)-
Autor(es): dc.contributorSanta Casa de São Paulo School of Medical Sciences-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorGuissoni Campos, Leila Maria-
Autor(es): dc.creatorCampanari, Gyovanna Sorrentino dos Santos-
Autor(es): dc.creatorSantiago, Jeferson-
Autor(es): dc.creatorSantos, Eduardo Vinicius Barboza-
Autor(es): dc.creatorSantos, Alana Cristy Ghiraldelli-
Autor(es): dc.creatorCabrini, Mayara Longui-
Autor(es): dc.creatorAudi, Mauro-
Autor(es): dc.creatorCosta, Isabela Bazzo-
Autor(es): dc.creatorEvangelista de Araujo, Viviane Canhizares-
Autor(es): dc.creatorBodra, Stephannie Monaco-
Autor(es): dc.creatorGualassi, Maressa Monteiro Pereira-
Autor(es): dc.creatorMotta-Teixeira, Lívia Clemente-
Autor(es): dc.creatorPinato, Luciana-
Data de aceite: dc.date.accessioned2025-08-21T22:58:03Z-
Data de disponibilização: dc.date.available2025-08-21T22:58:03Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3389/fnana.2024.1480971-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/307447-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/307447-
Descrição: dc.descriptionClock genes, which are essential for suprachiasmatic nucleus (SCN) function, also play critical roles in other brain regions, and their expression have been the subject of various studies. An increasingly deeper understanding of the expression of these genes in different species contributes to our knowledge of their functions and the factors influencing their expression. Considering that most studies have been conducted in nocturnal rodents, in this study we investigated the presence of Per1, Per2 and Cry1 in neurons of the substantia nigra (SN) and subthalamic nucleus (STN) in a diurnal primate. The immunoreactivity of Per1, Per2, and Cry1 was analyzed using immunohistochemistry, revealing significant Per1-IR, Per2-IR, and Cry1-IR in the SN. While Per1-IR and Per2-IR were also observed in the STN, no Cry1-IR staining was detected in the STN. These results confirm the presence of proteins that regulate circadian rhythms in areas associated with motor behavior.-
Descrição: dc.descriptionPostgraduate Program in Structural and Functional Interactions in Rehabilitation – UNIMAR School of Medicine Universidade de Marília (UNIMAR)-
Descrição: dc.descriptionSanta Casa de São Paulo School of Medical Sciences-
Descrição: dc.descriptionDepartment of Speech Language and Hearing Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Speech Language and Hearing Sciences São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationFrontiers in Neuroanatomy-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcircadian rhythms-
Palavras-chave: dc.subjectclock genes-
Palavras-chave: dc.subjectdopamine-
Palavras-chave: dc.subjectprimate-
Palavras-chave: dc.subjectsubstantia nigra-
Palavras-chave: dc.subjectsubthalamic nucleus-
Título: dc.titleCharacterization of clock proteins in the substantia nigra and subthalamic nucleus of the Sapajus apella primate-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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