Inflammatory Profile of Different Absorbable Membranes Used for Bone Regeneration: An In Vivo Study

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorBizelli, Vinícius Ferreira-
Autor(es): dc.creatorAlécio Viotto, Arthur Henrique-
Autor(es): dc.creatorDelamura, Izabela Fornazari-
Autor(es): dc.creatorBaggio, Ana Maira Pereira-
Autor(es): dc.creatorRamos, Edith Umasi-
Autor(es): dc.creatorFaverani, Leonardo Perez-
Autor(es): dc.creatorBassi, Ana Paula Farnezi-
Data de aceite: dc.date.accessioned2025-08-21T20:22:32Z-
Data de disponibilização: dc.date.available2025-08-21T20:22:32Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/biomimetics9070431-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/307363-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/307363-
Descrição: dc.descriptionBackground: Guided bone regeneration (GBR) has become a necessary practice in implantology. Absorbable membranes have shown advantages over non-absorbable membranes, such as blood support of bone tissue. This study aimed to evaluate five collagen membranes in rat calvaria critical-size defects through a histomorphometric analysis of the inflammatory profile during the initial phase of bone repair. Materials and methods: A total of 72 Albinus Wistar rats were used for the study, divided into six groups, with 12 animals per group, and two experimental periods, 7 and 15 days. The groups were as follows: the CG (clot), BG (Bio-Gide®), JS (Jason®), CS (Collprotect®), GD (GemDerm®), and GDF (GemDerm Flex®). Results: Data showed that the BG group demonstrated an inflammatory profile with an ideal number of inflammatory cells and blood vessels, indicating a statistically significant difference between the JS and CS groups and the BG group in terms of the number of inflammatory cells and a statistically significant difference between the JS and CS groups and the GD group in terms of angiogenesis (p < 0.05). Conclusions: We conclude that different origins and ways of obtaining them, as well as the thickness of the membrane, can interfere with the biological response of the material.-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University UNESP, SP-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery School of Dentistry São Paulo State University UNESP, SP-
Idioma: dc.languageen-
Relação: dc.relationBiomimetics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectangiogenesis-
Palavras-chave: dc.subjectbiomaterials-
Palavras-chave: dc.subjectbone regeneration-
Título: dc.titleInflammatory Profile of Different Absorbable Membranes Used for Bone Regeneration: An In Vivo Study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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