Effects of Platelet-Rich Fibrin on Bone Healing Around Implants Placed in Maxillary Sinuses: A Histomorphometric Assessment in Rabbits

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorTel-Aviv-
Autor(es): dc.contributorRambam Health Care Campus-
Autor(es): dc.contributorGuarulhos University-
Autor(es): dc.contributorUNISAGRADO-
Autor(es): dc.contributorTufts University-
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.creatorGrossi-Oliveira, Gustavo Augusto-
Autor(es): dc.creatorDallazen, Eduardo-
Autor(es): dc.creatorAsbi, Thabet-
Autor(es): dc.creatorFonseca-Santos, João Matheus-
Autor(es): dc.creatorRibeiro-Júnior, Paulo Domingos-
Autor(es): dc.creatorShibli, Jamil A.-
Autor(es): dc.creatorMassari Grecco, Cinthya-
Autor(es): dc.creatorMagro-Filho, Osvaldo-
Autor(es): dc.creatorMourão, Carlos Fernando-
Autor(es): dc.creatorHaim, Doron-
Autor(es): dc.creatorMayer, Yaniv-
Autor(es): dc.creatorFaverani, Leonardo P.-
Data de aceite: dc.date.accessioned2025-08-21T18:30:01Z-
Data de disponibilização: dc.date.available2025-08-21T18:30:01Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/jfb15120375-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/307311-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/307311-
Descrição: dc.descriptionThis study investigated the effect of platelet-rich fibrin (PRF) on bone healing around implants placed in elevated sinus cavities. Forty New Zealand albino rabbits were divided into eight groups, based on the time of sacrifice (14 or 40 days) and the material used: blood clot (control), hydroxyapatite (HA) from bovine bone, HA combined with PRF, and PRF alone. Each group consisted of five animals (n = 5). A histological analysis measured bone-to-implant contact (BIC) and bone area fraction occupancy (BAFO). The results showed significant increases in the BIC and BAFO values at 40 days compared to 14 days in most groups. At day 14, the HA+PRF group had higher BIC than the clot and the PRF alone groups. At 40 days, HA+PRF maintained the highest BIC across all groups (p < 0.05), though it did not show an advantage for BAFO. These findings indicate that combining HA with PRF promotes better osseointegration around implants placed immediately in maxillary sinus augmentation. Given the limited research on PRF’s biological impact, these results underscore the importance of evaluating PRF’s role in peri-implant healing and its potential benefits for clinical use in sinus augmentation.-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Division of Oral and Maxillofacial Surgery and Implantology School of Dentistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionMaccabi-Dent Research Department Tel-Aviv-
Descrição: dc.descriptionDepartment of Periodontology Rambam Health Care Campus-
Descrição: dc.descriptionDepartment of Periodontology Dental Research Division Guarulhos University, SP-
Descrição: dc.descriptionDivision of Oral and Maxillofacial Surgery and Implantology School of Dentistry UNISAGRADO, SP-
Descrição: dc.descriptionDepartment of Basic and Clinical Translational Sciences School of Dental Medicine Tufts University-
Descrição: dc.descriptionDepartment of Oral Diagnosis Division of Oral and Maxillofacial Surgery Piracicaba Dental School University of Campinas (UNICAMP), SP-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery Division of Oral and Maxillofacial Surgery and Implantology School of Dentistry São Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Functional Biomaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectalveolar bone loss-
Palavras-chave: dc.subjectbone substitutes-
Palavras-chave: dc.subjectdental implants-
Palavras-chave: dc.subjectplatelet-rich fibrin-
Título: dc.titleEffects of Platelet-Rich Fibrin on Bone Healing Around Implants Placed in Maxillary Sinuses: A Histomorphometric Assessment in Rabbits-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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