Biocomposite-based fibrous scaffolds of natural rubber/polyhydroxybutyrate blend reinforced with 45S5 bioglass aiming at biomedical applications

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Illinois at Chicago (UIC)-
Autor(es): dc.contributorPolish Academy of Sciences-
Autor(es): dc.contributorKorea University-
Autor(es): dc.creatorSilva, Michael J.-
Autor(es): dc.creatorDias, Yasmin J.-
Autor(es): dc.creatorZaszczyńska, Angelika-
Autor(es): dc.creatorRobles, Jaqueline Rojas-
Autor(es): dc.creatorAbiade, Jeremiah-
Autor(es): dc.creatorKowalczyk, Tomasz-
Autor(es): dc.creatorKołbuk, Dorota-
Autor(es): dc.creatorSajkiewicz, Paweł Ł.-
Autor(es): dc.creatorYarin, Alexander L.-
Data de aceite: dc.date.accessioned2025-08-21T18:49:51Z-
Data de disponibilização: dc.date.available2025-08-21T18:49:51Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-01-19-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1002/pc.27839-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/306988-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/306988-
Descrição: dc.descriptionThe solution blow spinning technique was used to fabricate a new biocomposite fibrous mat consisting of natural rubber (NR) and polyhydroxybutyrate (PHB) bioblend, with various loads of 45S5 bioglass (BG) particles. According to SEM analysis, NR fibers exhibited ribbon-like morphologies, whereas the addition of PHB resulted in improved fiber formation and a reduction in their diameter. In NR-PHB/BG biocomposites with varying BG loadings, typical thermal degradation events of PHB (stage i) and NR (stage ii) were observed. In comparison with pure PHB, the TG/DTG curves of NR-PHB/BG specimens revealed a lower stage i degradation peak. Such an outcome is possibly due to the fact that PHB in the NR-PHB fibers is located predominantly at the surface, that is, PHB is more susceptible to thermal degradation. The NR-PHB/BG biocomposite possessed an increased stiffness due to the addition of PHB and BG, resulting in an increased stress and a decreased strain at rupture compared to the pure NR and NR-PHB mats. DMA analysis revealed two well-defined regions, above and below the glass transition temperature (Tg), for the storage modulus (E') of the NR-PHB/BG specimens. The values of E' were in both regions for NR-PHB/BG specimens increased at higher BG content. The measured tanδ = E″/E' was used to determine the Tg value for all specimens, with Tg found to be in the −49 to −46°C range. Finally, NR-PHB/BG biocomposite fibrous were proven noncytotoxic by in-vitro testing on fibroblasts. These biocomposites enhanced cell growth, holding great promise for tissue engineering applications. Highlights: Solution blow spinning technique was used to produce three-phase biocomposite specimens. NR-PHB/BG fibrous mat specimens with a diameter of 9–10 μm were obtained. Although high BG loads are applied to the NR-PHB/BG specimens, they remain elastic and flexible. Fibrous biocomposite mats enhance cell growth and possess great potential for tissue engineering.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionNarodowa Agencja Wymiany Akademickiej-
Descrição: dc.descriptionFaculty of Engineering and Science Department of Engineering São Paulo State University (UNESP)-
Descrição: dc.descriptionDepartment of Mechanical and Industrial Engineering University of Illinois at Chicago (UIC)-
Descrição: dc.descriptionInstitute of Fundamental Technological Research Polish Academy of Sciences-
Descrição: dc.descriptionSchool of Mechanical Engineering Korea University-
Descrição: dc.descriptionFaculty of Engineering and Science Department of Engineering São Paulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2021/10512-5-
Descrição: dc.descriptionNarodowa Agencja Wymiany Akademickiej: PPI/APM/2018/1/00045/U/001-
Formato: dc.format1107-1127-
Idioma: dc.languageen-
Relação: dc.relationPolymer Composites-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject45S5 bioglass-
Palavras-chave: dc.subjectbiocomposite fibrous mat-
Palavras-chave: dc.subjectbiomedical applications-
Palavras-chave: dc.subjectnatural rubber-
Palavras-chave: dc.subjectpolyhydroxybutyrate-
Palavras-chave: dc.subjectsolution blow spinning-
Título: dc.titleBiocomposite-based fibrous scaffolds of natural rubber/polyhydroxybutyrate blend reinforced with 45S5 bioglass aiming at biomedical applications-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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