Coated Biodegradable Zinc Lithium Alloys: Development and Characterization of Co-Doped Strontium Copper Tricalcium Phosphate Coating for Antimicrobial Applications

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Autor(es): dc.contributorConsiglio Nazionale delle Ricerche (ISM-CNR)-
Autor(es): dc.contributorI.M. Sechenov First Moscow State Medical University-
Autor(es): dc.contributorUniversità della Basilicata-
Autor(es): dc.contributorIstituto Zooprofilattico Sperimentale Lazio e Toscana “M. Aleandri”-
Autor(es): dc.contributorRussian Academy of Sciences-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorPeking University-
Autor(es): dc.creatorRau, Julietta V.-
Autor(es): dc.creatorDe Bonis, Angela-
Autor(es): dc.creatorCurcio, Mariangela-
Autor(es): dc.creatorBarbaro, Katia-
Autor(es): dc.creatorFosca, Marco-
Autor(es): dc.creatorFadeeva, Inna V.-
Autor(es): dc.creatorCardoso, Giovana Collombaro-
Autor(es): dc.creatorTeghil, Roberto-
Autor(es): dc.creatorSlonskaya, Tatiana K.-
Autor(es): dc.creatorZheng, Yufeng-
Data de aceite: dc.date.accessioned2025-08-21T21:02:08Z-
Data de disponibilização: dc.date.available2025-08-21T21:02:08Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-08-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/coatings14081073-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/306739-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/306739-
Descrição: dc.descriptionZinc biodegradable implants represent a revolutionary advancement in medical technology, offering a promising alternative to titanium and stainless-steel implants and avoiding the need for secondary surgeries for removal. In this study, we aimed to fulfil the clinical demand for biodegradable implant materials by applying a coating of double-doped strontium and copper resorbable tricalcium phosphate (SrCu-TCP) onto a zinc-lithium (Zn-Li) biodegradable alloy using the Pulsed Laser Deposition method. The coated surfaces were thoroughly characterized using X-ray Diffraction, Fourier Transform Infrared Spectroscopy, Atomic Force Microscopy, and Scanning Electron Microscopy coupled with Energy Dispersive X-ray. Microbiology experiments were conducted to assess the inhibitory effects on the growth of various bacteria strains, including gram-positive Staphylococcus aureus and Enterococcus faecalis, gram-negative Pseudomonas aeruginosa and Escherichia coli, as well as the fungus Candida albicans. The obtained results showed that the roughness of the Zn-Li alloy increased from 91.8 ± 29.4 to 651.0 ± 179.5 nm when coated with SrCu-TCP. The thickness of the coating ranged between 3–3.5 µm. The inhibition of growth for all four bacteria strains and the fungus was in the range of 24–35% when cultured on SrCu-TCP coated Zn-Li samples. These findings suggest that the developed coatings are promising candidates for applications requiring inhibition of microorganisms.-
Descrição: dc.descriptionIstituto di Struttura della Materia Consiglio Nazionale delle Ricerche (ISM-CNR), Via del Fosso del Cavaliere 100-
Descrição: dc.descriptionDepartment of Analytical Physical and Colloid Chemistry Institute of Pharmacy I.M. Sechenov First Moscow State Medical University, Trubetskaya 8, Build. 2-
Descrição: dc.descriptionDipartimento di Scienze Università della Basilicata, Via dell’Ateneo Lucano 10-
Descrição: dc.descriptionIstituto Zooprofilattico Sperimentale Lazio e Toscana “M. Aleandri”, Via Appia Nuova-
Descrição: dc.descriptionA.A. Baikov Institute of Metallurgy and Material Science Russian Academy of Sciences, Leninsky 49-
Descrição: dc.descriptionLaboratório de Anelasticidade e Biomateriais UNESP—Universidade Estadual Paulista, SP-
Descrição: dc.descriptionSchool of Materials Science and Engineering Peking University, No. 5 Yi-He-Yuan Road, Hai-Dian District-
Descrição: dc.descriptionLaboratório de Anelasticidade e Biomateriais UNESP—Universidade Estadual Paulista, SP-
Idioma: dc.languageen-
Relação: dc.relationCoatings-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiodegradable alloys-
Palavras-chave: dc.subjectbiodegradable coatings-
Palavras-chave: dc.subjectcoatings-
Palavras-chave: dc.subjectcopper and strontium co-doped tricalcium phosphate-
Palavras-chave: dc.subjectcopper and strontium doped tricalcium phosphate-
Palavras-chave: dc.subjecttricalcium phosphate coatings-
Palavras-chave: dc.subjectZn-Li alloy-
Título: dc.titleCoated Biodegradable Zinc Lithium Alloys: Development and Characterization of Co-Doped Strontium Copper Tricalcium Phosphate Coating for Antimicrobial Applications-
Tipo de arquivo: dc.typelivro digital-
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