Assessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorFederal University of Campina Grande (UFCG)-
Autor(es): dc.contributorAnimal Care Barueri Veterinary Clinic-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorIPEN/CNEN)-
Autor(es): dc.creatorGarcia, Daniel Cardoso-
Autor(es): dc.creatorMingrone, Larissa Eckmann-
Autor(es): dc.creatorPinotti, Felipe Eduardo-
Autor(es): dc.creatorSeade, Leonardo-
Autor(es): dc.creatorMelo, Rosane de-
Autor(es): dc.creatorLugão, Ademar Benévolo-
Autor(es): dc.creatorBezerra, José Artur Brilhante-
Autor(es): dc.creatorSá, Marcelo Jorge Cavalcanti de-
Data de aceite: dc.date.accessioned2025-08-21T17:12:26Z-
Data de disponibilização: dc.date.available2025-08-21T17:12:26Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/vetsci12030200-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/306694-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/306694-
Descrição: dc.descriptionAutografts, allografts, and synthetic bone substitutes are essential in reconstructive orthopedic surgery. Although autografts and allografts provide excellent skeletal integration, their use is limited by host morbidity and graft acquisition challenges. Synthetic materials like β-tricalcium phosphate (β-TCP) offer promising osseoconductive properties as a potential substitute. This study evaluated the osseointegration of β-TCP ceramic cylinder implants in bone defects in rabbits. Eighteen New Zealand rabbits underwent radial diaphysis ostectomy to create a critical segmental defect and were divided into three groups: Group A received β-TCP blocks, Group B received allogenous cortical bone grafts, and Group C underwent ostectomy without defect filling. Postoperative assessments included clinical evaluations, radiographs, micro-computed tomography, and histology at various time points to assess osseointegration and implant resorption. At the 120th postoperative day, Group B showed successful bone integration without infection. In contrast, Group A showed no osseointegration or resorption of the β-TCP implants, and Group C exhibited bone non-union. While β-TCP demonstrated biocompatibility, it lacked osseoconductivity, likely due to low porosity. β-TCP implants did not promote bone consolidation, suggesting that further research on porosity and shape is needed to improve their suitability for veterinary orthopedic reconstructive surgery.-
Descrição: dc.descriptionDepartment of Surgery Faculty of Veterinary Medicine Federal University of Campina Grande (UFCG)-
Descrição: dc.descriptionDepartment of Surgery Animal Care Barueri Veterinary Clinic-
Descrição: dc.descriptionDepartment of Surgery School of Dentistry São Paulo State University (UNESP)-
Descrição: dc.descriptionBiomaterials Laboratory Institute for Energy and Nuclear Research National Nuclear Energy Commission IPEN/CNEN), São Paulo-
Descrição: dc.descriptionDepartment of Surgery School of Dentistry São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationVeterinary Sciences-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectbiomaterial-
Palavras-chave: dc.subjectbone critical defect-
Palavras-chave: dc.subjectbone implant-
Palavras-chave: dc.subjectbone segmental defect-
Título: dc.titleAssessment of the Osseointegration of Pure-Phase β-Tricalcium Phosphate (β-TCP) Ceramic Cylinder Implants in Critical Segmental Radial Bone Defects in Rabbits-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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