The Impact in Intestines and Microbiota in BALB/c Mice Through Consumption of Milk Fermented by Potentially Probiotic Lacticaseibacillus casei SJRP38 and Limosilactobacillus fermentum SJRP43

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Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAraraquara City Hall-
Autor(es): dc.creatorde Souza, Bruna Maria Salotti-
Autor(es): dc.creatorGuerra, Luiz Henrique Alves-
Autor(es): dc.creatorVarallo, Giovanna Rossi-
Autor(es): dc.creatorTaboga, Sebastião Roberto-
Autor(es): dc.creatorPenna, Ana Lúcia Barretto-
Data de aceite: dc.date.accessioned2025-08-21T19:26:04Z-
Data de disponibilização: dc.date.available2025-08-21T19:26:04Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s12602-023-10158-3-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/306681-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/306681-
Descrição: dc.descriptionThe present study aimed to evaluate the effect of consumption of milk fermented by Lacticaseibacillus (Lc.) casei SJRP38 and Limosilactobacillus (Lm.) fermentum SJRP43 on bacterial translocation, stool analysis, and intestinal morphology of healthy BALB/c mice. Potentially probiotic lactic acid bacteria, Lc. casei SJRP38, and Lm. fermentum SJRP43 were evaluated and analyzed for translocation, fecal analysis, and intestinal morphology of four groups of mice: water control (WC), milk control (MC), milk fermented by Lc. casei SJRP38 (FMLC), and milk fermented by Lm. fermentum SJRP43 (FMLF), in co-culture with Streptococcus thermophilus ST080. The results of the animal assay indicate that the population of Lactobacilli and Bidobacterium sp. in the gastrointestinal tract of BALB/c mice was greater than 6.0 log10 CFU/g, and there was no evidence of bacteremia due to the low incidence of bacterial translocation. Ingesting fermented milk containing Lc. casei SJRP38 and Lm. fermentum SJRP43 was found to promote a healthier microbiota, as it led to a reduction in Clostridium sp. and an increase in Lactobacilli and Bifidobacterium sp. in feces. Furthermore, the dairy treatments (MC, FMLC, and FMLF) resulted in taller intestinal villi and an increase in the frequency of goblet cells in the intestines. Overall, the consumption of fermented milk containing Lc. casei SJRP38 and Lm. fermentum SJRP43 strains was deemed safe and demonstrated beneficial effects on the intestines of BALB/c mice.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionDepartment of Technology and Inspection of Products of Animal Origin UFMG - Federal University of Minas Gerais, MG-
Descrição: dc.descriptionDepartment of Biology Institute of Biosciences Languages and Exact Sciences UNESP - Sao Paulo State University, SP-
Descrição: dc.descriptionAraraquara City Hall, SP-
Descrição: dc.descriptionDepartment of Food Engineering and Technology Institute of Biosciences Languages and Exact Sciences UNESP - Sao Paulo State University, SP-
Descrição: dc.descriptionDepartment of Biology Institute of Biosciences Languages and Exact Sciences UNESP - Sao Paulo State University, SP-
Descrição: dc.descriptionDepartment of Food Engineering and Technology Institute of Biosciences Languages and Exact Sciences UNESP - Sao Paulo State University, SP-
Descrição: dc.descriptionCNPq: Project 313909/2020-2-
Formato: dc.format462-478-
Idioma: dc.languageen-
Relação: dc.relationProbiotics and Antimicrobial Proteins-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectFunctional food-
Palavras-chave: dc.subjectGastrointestinal tract-
Palavras-chave: dc.subjectHistology-
Palavras-chave: dc.subjectIntestinal morphometry-
Palavras-chave: dc.subjectLactic acid bacteria-
Título: dc.titleThe Impact in Intestines and Microbiota in BALB/c Mice Through Consumption of Milk Fermented by Potentially Probiotic Lacticaseibacillus casei SJRP38 and Limosilactobacillus fermentum SJRP43-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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