Physical status, symptoms and health-related quality of life during a severe exacerbation of COPD: Recovery and discriminative capacity for future events

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorHasselt University-
Autor(es): dc.contributorUniversity of Aveiro-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorZiekenhuis Oost-Limburg-
Autor(es): dc.contributorCenter of Expertise for Chronic Organ Failure-
Autor(es): dc.contributorMaastricht University Medical Centre-
Autor(es): dc.creatorQuadflieg, Kirsten-
Autor(es): dc.creatorMachado, Ana-
Autor(es): dc.creatorde Lima, Fabiano Francisco-
Autor(es): dc.creatorDederen, Anand-
Autor(es): dc.creatorDaenen, Marc-
Autor(es): dc.creatorRuttens, David-
Autor(es): dc.creatorThomeer, Michiel-
Autor(es): dc.creatorSpruit, Martijn A.-
Autor(es): dc.creatorBurtin, Chris-
Data de aceite: dc.date.accessioned2025-08-21T23:02:21Z-
Data de disponibilização: dc.date.available2025-08-21T23:02:21Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.rmed.2023.107437-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/306165-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/306165-
Descrição: dc.descriptionObjective: Severe acute exacerbations of chronic obstructive pulmonary disease (AECOPD) can have a negative impact on functional capacity, symptoms and health-related quality of life (HRQOL). This study aimed to i) investigate the recovery of muscle strength, functional capacity, symptoms, and HRQOL in patients after a severe AECOPD; ii) compare with matched patients with stable COPD (SCOPD); and iii) assess whether these assessments at hospital discharge could discriminate patients’ risk for future events. Methods: This observational study assessed patients with AECOPD during hospital discharge (T1) and one month after discharge (T2). Patients with SCOPD were assessed once. Quadriceps force, handgrip strength, short physical performance battery (SPPB), 6-min walk distance (6 MWD), COPD assessment test (CAT), London chest activity of daily living (LCADL), modified medical research council, checklist individual strength-fatigue, patient health questionnaire, and physical activity (Actigraph) were measured. Exacerbation-related readmission and mortality within six months and 1-year were collected. Results: Forty-four patients with AECOPD were matched with 44 patients with SCOPD. At T2, a significant improvement was found for the SPPB total score, 6 MWD, CAT score, and LCADL score. Compared to patients with SCOPD, a worse LCADL score was found at T2 in patients with AECOPD. Patients with AECOPD that were readmitted or died had a worse SPPB classification and five-repetition sit-to-stand test at T1. Conclusion: Patients after severe AECOPD improved in functional capacity and HRQOL one month after hospital discharge, but ADL performance was still worse compared to SCOPD. Patients who were readmitted or died had significantly worse scores on functional tests at hospital discharge.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniversiteit Hasselt-
Descrição: dc.descriptionREVAL – Rehabilitation Research Center BIOMED – Biomedical Research Institute Faculty of Rehabilitation Sciences Hasselt University-
Descrição: dc.descriptionRespiratory Research and Rehabilitation Laboratory (Lab 3R) School of Health Sciences (ESSUA) Institute of Biomedicine (iBiMED) Department of Medical Sciences University of Aveiro-
Descrição: dc.descriptionDepartment of Physical Therapy SãoPaulo State University (UNESP)-
Descrição: dc.descriptionDepartment Lung Diseases Ziekenhuis Oost-Limburg-
Descrição: dc.descriptionFaculty of Medicine and Life Sciences Hasselt University-
Descrição: dc.descriptionCIRO Center of Expertise for Chronic Organ Failure Department of Research and Education-
Descrição: dc.descriptionDepartment of Respiratory Medicine NUTRIM School of Nutrition and Translational Research in Metabolism Faculty of Health Medicine and Life Sciences Maastricht University Medical Centre-
Descrição: dc.descriptionDepartment of Physical Therapy SãoPaulo State University (UNESP)-
Descrição: dc.descriptionFAPESP: 2019/10744–3-
Descrição: dc.descriptionUniversiteit Hasselt: DOC/SCHL-BOSE/190/522-
Idioma: dc.languageen-
Relação: dc.relationRespiratory Medicine-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCOPD-
Palavras-chave: dc.subjectExacerbation-
Palavras-chave: dc.subjectHospitalization-
Palavras-chave: dc.subjectMortality-
Palavras-chave: dc.subjectReadmission-
Título: dc.titlePhysical status, symptoms and health-related quality of life during a severe exacerbation of COPD: Recovery and discriminative capacity for future events-
Tipo de arquivo: dc.typelivro digital-
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