Guinea Pigs Develop Cutaneous Basophilia after Repeated Infestations by Nymphs of the Tick Amblyomma triste

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorOtavio, Flavio S.-
Autor(es): dc.creatorBechara, Gervasio Henrique-
Data de aceite: dc.date.accessioned2021-03-10T16:36:47Z-
Data de disponibilização: dc.date.available2021-03-10T16:36:47Z-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2014-05-20-
Data de envio: dc.date.issued2008-01-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1196/annals.1428.027-
Fonte completa do material: dc.identifierhttp://hdl.handle.net/11449/3054-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/3054-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionEuropean Commission-
Descrição: dc.descriptionEuropean Commission: 510561-
Descrição: dc.descriptionThis study investigated the development of resistance in guinea pigs to nymphs of Amblyomma triste ticks after repeated infestations. Guinea pigs were infested thrice, at 30-day intervals, with 30 nymphs of A. triste per animal per infestation. Acquisition of resistance was evaluated by determining: nymph yielding rate, engorgement period, and weight. Skin biopsies of tick bite sites were collected at 24, 48, and 96 h after tick attachment for inflammatory cell counts. Engorged nymphs weighed 5.53 mg +/- 1.9 in re-infested hosts (56.6% less than in primary infestation) and took 6.9 days +/- 2.16 to feed in the third infestation (14.5% more than in the first infestation). Guinea pigs yielded 78% +/- 7.2 of nymphs in the re-infestation (11.6% less than in the primary infestation). In addition, a marked increase in basophil influx was observed from the first infestation onward; 69% of infiltrated cells were basophils in re-infested hosts 24 h after tick attachment. No basophils were seen at this time in primary infested animals. That number increased to 84.7% 48 h post attachment in re-infested hosts (73.2% more than in the primary infested ones) and decreased markedly 96 h post attachment in both groups (2.6% and 1% of basophils in the third and first infestation, respectively). We conclude that guinea pigs acquire resistance against nymphs of A. triste ticks after repeated infestations and that a cutaneous basophilia must play a crucial role in such a mechanism.-
Formato: dc.format226-229-
Idioma: dc.languageen-
Publicador: dc.publisherBlackwell Publishing-
Relação: dc.relationAnimal Biodiversity and Emerging Diseases: Prediction and Prevention-
Relação: dc.relation4.277-
Relação: dc.relation2,108-
Direitos: dc.rightsclosedAccess-
Palavras-chave: dc.subjectcutaneous basophilia-
Palavras-chave: dc.subjectguinea pig-
Palavras-chave: dc.subjectAmblyomma triste nymphs-
Palavras-chave: dc.subjectbiological parameters-
Título: dc.titleGuinea Pigs Develop Cutaneous Basophilia after Repeated Infestations by Nymphs of the Tick Amblyomma triste-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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