Potential global cis and trans regulation of lncRNAs in Saccharomyces cerevisiae subjected to ethanol stress

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSchnepper, Amanda Piveta-
Autor(es): dc.creatorMarques, Lucas Farinazzo-
Autor(es): dc.creatorWolf, Ivan Rodrigo-
Autor(es): dc.creatorKubo, Agatha M.S.-
Autor(es): dc.creatorValente, Guilherme Targino-
Data de aceite: dc.date.accessioned2025-08-21T23:18:16Z-
Data de disponibilização: dc.date.available2025-08-21T23:18:16Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-08-20-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.gene.2024.148521-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/305499-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/305499-
Descrição: dc.descriptionLong noncoding RNAs (lncRNAs) are regulatory RNAs. Saccharomyces cerevisiae strains transcribe hundreds of lncRNAs. LncRNAs can regulate the expression of adjacent genes (cis-regulation) or distant genes from lncRNAs (trans-regulation). Here, we analyzed the potential global cis and trans-regulation of lncRNAs of yeast subjected to ethanol stress. For potential cis regulation, for BMA641-A and S288C strains, we observed that most lncRNA-neighbor gene pairs increased the expression at a certain point followed by a decrease, and vice versa. Based on the transcriptome profile and triple helix prediction between lncRNAs and promoters of coding genes, we observed nine different ways of potential trans regulation that work in a strain-specific manner. Our data provide an initial landscape of potential cis and trans regulation in yeast, which seems to be strain-specific.-
Descrição: dc.descriptionDepartment of Structural and Functional Biology Institute of Biosciences São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionDepartment of Bioprocess and Biotechnology School of Agriculture São Paulo State University (UNESP), SP-
Descrição: dc.descriptionLaboratory of Applied Biotechnology Sāo Paulo State University (UNESP), SP-
Descrição: dc.descriptionDepartment of Structural and Functional Biology Institute of Biosciences São Paulo State University (UNESP), São Paulo-
Descrição: dc.descriptionDepartment of Bioprocess and Biotechnology School of Agriculture São Paulo State University (UNESP), SP-
Descrição: dc.descriptionLaboratory of Applied Biotechnology Sāo Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationGene-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCis and trans regulation-
Palavras-chave: dc.subjectlncRNAs-
Palavras-chave: dc.subjectStrain-specificity-
Título: dc.titlePotential global cis and trans regulation of lncRNAs in Saccharomyces cerevisiae subjected to ethanol stress-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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