Histological changes in pulp-dentin complex in tooth subjected to traumatic occlusion and subluxation

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorDept. of Periodontics-
Autor(es): dc.creatorAmaral, Marina Fuzette-
Autor(es): dc.creatorCasatti, Cláudio Aparecido-
Autor(es): dc.creatorNaqvi, Afsar Raza-
Autor(es): dc.creatorDebortoli, Caio Vinicius Lourenço-
Autor(es): dc.creatorAtili Brandini, Daniela-
Data de aceite: dc.date.accessioned2025-08-21T19:43:34Z-
Data de disponibilização: dc.date.available2025-08-21T19:43:34Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.sdentj.2023.11.012-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/305027-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/305027-
Descrição: dc.descriptionBackground: This study evaluated the influence of traumatic occlusion in the dentin-pulp complex a molar teeth submitted to subluxation. Material and methods: Ninety Wistar rats were divided into groups Naïve (N), Subluxation (S) and Subluxation with traumatic occlusion (STO) and submitted to histological analysis after 7 and 21 days. A quantitative analysis was submitted to one-way ANOVA and Tukey's post-hoc test, and Chi-square and Bonferronís post-hoc test. Results: S and STO showed a significant increase in blood vessels area (p < 0.0005), amorphous fundamental substance (p < 0.0005) and reactionary dentin formation (p < 0.0005), as well as a decrease in the nuclear profile (p < 0.0005), odontoblast layer (p = 0.013 and p < 0.0005) by day 7 when compared with N. These changes normalized by day 21, except for the reactionary dentin (p < 0.0005) in both S and STO groups. Interestingly, the STO group exhibited significant changes in the increase of pulp calcification (p < 0.0005), presence of tubules with nuclei (p < 0.0005), and inflammatory infiltrate (p < 0.0005), as well reduction of nuclear profile (p < 0.0005), odontoblast layer (p < 0.0005) compared with N and S at day 21. Conclusions: STO impaired the defence response and decreased pulp regeneration capacity by increasing the inflammatory infiltrate and pulp calcification, and decreasing the nucleated cell number in the odontoblast layer and central pulp.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Physiology and Morphology São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionMucosal Immunology Lab The University of Illinois at Chicago College of Dentistry Dept. of Periodontics-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionDepartment of Physiology and Morphology São Paulo State University (UNESP) School of Dentistry-
Descrição: dc.descriptionFAPESP: 2012/03067-6-
Descrição: dc.descriptionFAPESP: 2017/15590-9-
Formato: dc.format321-327-
Idioma: dc.languageen-
Relação: dc.relationSaudi Dental Journal-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDental pulp-
Palavras-chave: dc.subjectRats-
Palavras-chave: dc.subjectTraumatic dental occlusion-
Palavras-chave: dc.subjectWounds and Injuries-
Título: dc.titleHistological changes in pulp-dentin complex in tooth subjected to traumatic occlusion and subluxation-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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