Efficacy of acellular xenogeneic dermal matrix graft in the treatment of multiple gingival recessions: systematic review and meta-analysis

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Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCentro Universitário Sagrado Coração- UNISAGRADO-
Autor(es): dc.creatorCosta, Matheus Souza Campos-
Autor(es): dc.creatorDaltro Rosa, Cléber Davi Del Rei-
Autor(es): dc.creatorBento, Victor Augusto Alves-
Autor(es): dc.creatorda Silva Costa, Sandy Maria-
Autor(es): dc.creatorSantiago, Joel Ferreira-
Autor(es): dc.creatorPellizzer, Eduardo Piza-
Autor(es): dc.creatorFraga de Almeida, Ana Lúcia Pompéia-
Data de aceite: dc.date.accessioned2025-08-21T19:51:14Z-
Data de disponibilização: dc.date.available2025-08-21T19:51:14Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s00784-024-05560-2-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304684-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304684-
Descrição: dc.descriptionObjective: This study aimed to compare the efficacy of acellular xenogeneic dermal matrix graft (AXDM) compared to connective tissue graft (CTG) in treating multiple gingival recessions. Materials and methods: A systematic search of electronic databases was conducted to identify randomized clinical trials (RCTs) that compared AXDM and CTG. The selected studies were subjected to bias risk assessment, data extraction, and meta-analyses. Parameters such as gingival recession height, width, mean percentage of root coverage, and complete root coverage were analyzed. Results: Seven RCTs involving 146 patients were included. The meta-analyses indicated that CTG was statistically superior to AXDM in reducing gingival recession height at the final follow-up (mean difference: -0.104 mm, 95% confidence interval [CI]: -0.180-0.028, p = 0.008) and width at the final follow-up (mean difference: -0.285 mm, 95% CI: -0.541-0.030, p = 0.029). CTG also demonstrated a significantly higher mean percentage of root coverage at the 6-month follow-up (difference in means: -2.761 mm, 95% CI: -4.932-0.590, p = 0.013) and a higher percentage of complete root coverage at the 6-month follow-up (odds Ratio [OR]: 0.598, 95% CI: 0.4-0.892, p = 0.012) compared to AXDM. However, there was no significant difference in the number of teeth with complete root coverage between CTG and AXDM (OR: 1.610, 95% CI: 0.983–2.636, p = 0.058) and aesthetic outcomes (mean difference: 0.148, 95% CI: -0.277-0.573, p = 0.494). Conclusions: CTG is more effective than AXDM in treating multiple gingival recessions. This is evidenced by significant reductions in gingival recession height and width, a higher mean percentage of root coverage, and a greater percentage of complete root coverage at the 6-month follow-up. Clinical relevance: In some clinical situations an alternative to CTG is required for the treatment of multiple gingival recessions. AXDM, despite presenting clinical outcomes that are not as satisfactory as CTG, can be used for this purpose.-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionDepartment of Prosthodontics and Periodontics Bauru School of Dentistry University of São Paulo (USP), 9-75, Vila Universitária, SP-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araçatuba Dental School São Paulo State University (UNESP), SP-
Descrição: dc.descriptionDepartament of Health Sciences School of Dentistry Centro Universitário Sagrado Coração- UNISAGRADO, SP-
Descrição: dc.descriptionDepartment of Prosthodontics and Periodontics Bauru School of Dentistry University of São Paulo (USP) and Hospital for Rehabilitation of Craniofacial Anomalies (HRAC) University of São Paulo, SP-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthodontics Araçatuba Dental School São Paulo State University (UNESP), SP-
Descrição: dc.descriptionCAPES: 001-
Idioma: dc.languageen-
Relação: dc.relationClinical Oral Investigations-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectConnective tissue-
Palavras-chave: dc.subjectGingival recession-
Palavras-chave: dc.subjectRoot coverage techniques-
Palavras-chave: dc.subjectXenografts-
Título: dc.titleEfficacy of acellular xenogeneic dermal matrix graft in the treatment of multiple gingival recessions: systematic review and meta-analysis-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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