Hydrodynamic comparison of different geometries of square cross-section airlift bioreactor using computational fluid dynamics

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorScience and Technology of São Paulo-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorEsperança, Mateus N.-
Autor(es): dc.creatorCerri, Marcel O.-
Autor(es): dc.creatorMazziero, Vítor T.-
Autor(es): dc.creatorBéttega, Rodrigo-
Autor(es): dc.creatorBadino, Alberto C.-
Data de aceite: dc.date.accessioned2025-08-21T21:16:18Z-
Data de disponibilização: dc.date.available2025-08-21T21:16:18Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1515/ijcre-2023-0010-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304648-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304648-
Descrição: dc.descriptionThe hydrodynamics of airlift bioreactors, which offer an interesting alternative to conventional stirred-tank bioreactors, has generally been evaluated using experimental approaches, requiring time, energy, and reagents. However, computational fluid dynamics (CFD) has emerged as an important and valuable tool for the analysis and design of these devices, saving time and experimental effort, while providing a large amount of information. In this study, four geometries of a square cross-section 10-L split airlift bioreactor operating with distilled water were simulated using CFD, and the hydrodynamics variables gas hold-up and liquid velocity were evaluated. CFD satisfactorily predicted the hydrodynamic parameters, when compared to experimental data, allowing adequate prediction of the shear rate distribution in airlift bioreactors. The results indicated that different shear rate distributions were obtained by geometric modifications in the bioreactor, showing that its design should be considered to satisfy different specific bioprocess requirements.-
Descrição: dc.descriptionFederal Institute of Education Science and Technology of São Paulo, Campus Capivari, SP-
Descrição: dc.descriptionFaculty of Pharmaceutical Sciences Department of Bioprocesses Engineering and Biotechnology São Paulo State University (UNESP), SP-
Descrição: dc.descriptionGraduate Program of Chemical Engineering Federal University of São Carlos, C.P. 676, SP-
Descrição: dc.descriptionFaculty of Pharmaceutical Sciences Department of Bioprocesses Engineering and Biotechnology São Paulo State University (UNESP), SP-
Formato: dc.format1291-1303-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Chemical Reactor Engineering-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectairlift bioreactor-
Palavras-chave: dc.subjectcomputational fluid dynamics-
Palavras-chave: dc.subjectgas hold-up-
Palavras-chave: dc.subjecthydrodynamic-
Palavras-chave: dc.subjectshear rate-
Título: dc.titleHydrodynamic comparison of different geometries of square cross-section airlift bioreactor using computational fluid dynamics-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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