Inflammatory cytokines and chemokines in obese adolescents with antibody against to adenovirus 36

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorSanches, Marcelo D’Alessandre-
Autor(es): dc.creatorGoldberg, Tamara Beres Lederer-
Autor(es): dc.creatorRizzo, Anapaula da Conceição Bisi-
Autor(es): dc.creatorda Silva, Valéria Nóbrega-
Autor(es): dc.creatorMosca, Luciana Nunes-
Autor(es): dc.creatorRomagnoli, Graziela Gorete-
Autor(es): dc.creatorGorgulho, Carolina Mendonça-
Autor(es): dc.creatorAraujo Junior, João Pessoa-
Autor(es): dc.creatorde Lima, Gustavo Ramos-
Autor(es): dc.creatorBetti, Isabella Rodrigues-
Autor(es): dc.creatorKurokawa, Cilmery Suemi-
Data de aceite: dc.date.accessioned2025-08-21T18:29:25Z-
Data de disponibilização: dc.date.available2025-08-21T18:29:25Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-11-30-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1038/s41598-023-33084-4-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304588-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304588-
Descrição: dc.descriptionObesity in adolescents has reached epidemic proportions and is associated with the inflammatory response and viral infections. The aim of this study was to understand the profile of inflammatory cytokines and chemokines associated with the inflammatory response and metabolic syndrome (MetS) in obese adolescents with positive serology for adenovirus 36 (ADV36). Thirty-six overweight, 36 obese, and 25 severe obesity adolescents aged 10 to 16 years were included in the study. The following variables were analyzed: sex, age, body mass index (BMI), blood pressure, total cholesterol and fractions, triglycerides, glucose, serum cytokine concentrations, and ADV36 antibodies. Cytokines and chemokines were quantified by cytometry and ADV36 serology was determined by enzyme-linked immunosorbent assay (ELISA). The results showed higher levels of the cytokines interleukin-1beta (IL-1β), IL-6, IL-10 and of the chemokine interferon-gamma-inducible protein 10 (IP-10) in severe obesity adolescents compared to the obese and overweight groups, as well as in the group with MetS compared to the group without this syndrome. The frequency of ADV36-positive individuals did not differ between groups. The findings revealed differences in BMI between the obese and severe obesity groups versus the overweight group in the presence of positivity for ADV36, suggesting an association with weight gain and possibly MetS installation.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionMedical School São Paulo State University (Unesp)-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University (Unesp)-
Descrição: dc.descriptionMedical School São Paulo State University (Unesp)-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University (Unesp)-
Descrição: dc.descriptionFAPESP: 14/24345-0-
Idioma: dc.languageen-
Relação: dc.relationScientific Reports-
???dc.source???: dc.sourceScopus-
Título: dc.titleInflammatory cytokines and chemokines in obese adolescents with antibody against to adenovirus 36-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.