Iron-related markers of inflammation in horses with colic

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCentro Universitário Moura Lacerda-
Autor(es): dc.creatorCanola, P. A.-
Autor(es): dc.creatorSalles, R.F. de-
Autor(es): dc.creatorDaneze, E. R.-
Autor(es): dc.creatorSobreira, M. F.R.-
Autor(es): dc.creatorOliveira, B.E. de-
Autor(es): dc.creatorFavero, M. L.-
Autor(es): dc.creatorAntonioli, M. L.-
Data de aceite: dc.date.accessioned2025-08-21T16:27:09Z-
Data de disponibilização: dc.date.available2025-08-21T16:27:09Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.jevs.2024.105010-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304345-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304345-
Descrição: dc.descriptionThe aim of the study was to compare and correlate levels of ferritin, transferrin, iron and APPs in healthy horses and those surgically treated for strangulating colic. On admission, measurements of inflammatory markers related to iron and total protein, fibrinogen, albumin, haptoglobin and ceruloplasmin were made. The study comprised 22 horses, divided into a control group (CG) of healthy horses (n = 10) and horses with surgically treated acute abdomen (n = 12), obstruction group (OG). The OG was subdivided according to the affected intestinal segment (small vs. large) and according to outcome (survivors vs. non survivors). The OG had higher haptoglobin (34.8±14.2 mg/dL vs 20.8±7.21 mg/dL) and transferrin (487±161 mg/dL vs 369±71.4 mg/dL) values and lower iron (96.9±65 µg/dL vs 218±105 µg/dL) values than the CG. The OG horses with large intestine obstruction had lower values of transferrin (374.6±130 mg/dL) than horses with small intestinal obstruction (598.6±98.9 mg/dL). There was no difference in outcome between horses with large and small intestinal obstruction. Ferritin levels were moderately correlated with total protein (r = 0.594; P = 0.042) and albumin (r = 0.584; P = 0.046) in OG. In the multivariate exploratory analysis, fibrinogen levels were higher in animals that did not survive. In conclusion, haptoglobin, transferrin and iron were useful inflammatory markers for colic in horses. The correlation of ferritin with other APPs shows a possible role of ferritin as an APP in horses. Fibrinogen levels are higher in horses with greater risk of death from strangulating obstructions.-
Descrição: dc.descriptionDepartment of Veterinary Medicine and Surgery São Paulo State University (Unesp) School of Agricultural and Veterinarian Sciences, Via de Acesso Prof. Paulo Donato Castellane, São Paulo-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Agricultural and Veterinarian Sciences, São Paulo-
Descrição: dc.descriptionCentro Universitário Moura Lacerda, São Paulo-
Descrição: dc.descriptionDepartment of Veterinary Medicine and Surgery São Paulo State University (Unesp) School of Agricultural and Veterinarian Sciences, Via de Acesso Prof. Paulo Donato Castellane, São Paulo-
Descrição: dc.descriptionSão Paulo State University (Unesp) School of Agricultural and Veterinarian Sciences, São Paulo-
Idioma: dc.languageen-
Relação: dc.relationJournal of Equine Veterinary Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCeliotomy-
Palavras-chave: dc.subjectEquine-
Palavras-chave: dc.subjectFerritin-
Palavras-chave: dc.subjectIron-
Palavras-chave: dc.subjectTransferrin-
Título: dc.titleIron-related markers of inflammation in horses with colic-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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