Molecular markers of mitochondrial intoxication

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCenter for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Autor(es): dc.creatorSeloto, Danielle Gabriel-
Autor(es): dc.creatorRizzi, Joyce Santana-
Autor(es): dc.creatorLima, Thania Rios Rossi-
Autor(es): dc.creatorPereira, Lílian Cristina-
Data de aceite: dc.date.accessioned2025-08-21T22:42:25Z-
Data de disponibilização: dc.date.available2025-08-21T22:42:25Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2021-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/B978-0-323-88462-4.00033-X-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304291-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304291-
Descrição: dc.descriptionMitochondria perform several biological functions in living organisms, such as ATP production; calcium, copper, and iron homeostasis; pyrimidine and steroid synthesis; thermogenesis; and calcium signaling. Xenobiotics have high affinity for compounds and present different potentials. When xenobiotics are present in the mitochondrial membrane, they lead to various disturbances and cause the organelle to collapse, altering the electron transport chain and resulting in loss of energy production and even cell death. Due to their structural and functional characteristics and because they can act as biosensors, mitochondria are important targets for assessing the toxicity of xenobiotics. Many methods, including colorimetry and fluorimetry, among others, can be used to clarify the mechanisms that induce mitochondrial damage and will be addressed throughout this chapter.-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School-
Descrição: dc.descriptionCenter for Evaluation of Environmental Impact on Human Health (TOXICAM)-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Agriculture-
Descrição: dc.descriptionSão Paulo State University (UNESP) Medical School-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Agriculture-
Formato: dc.format29-47-
Idioma: dc.languageen-
Relação: dc.relationMitochondrial Intoxication-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectIntoxication-
Palavras-chave: dc.subjectMechanisms of toxicity-
Palavras-chave: dc.subjectMitochondrial markers-
Palavras-chave: dc.subjectRONS production-
Título: dc.titleMolecular markers of mitochondrial intoxication-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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