Non-dipping circadian pattern as a predictor of incipient nephropathy in normotensive normoalbuminuric type 1 diabetics

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorJorge da Silva Franco, Roberto-
Autor(es): dc.creatorAntonio Vieira Filho, José-
Autor(es): dc.creatorInomata Cardoso da Silva, Douglas-
Autor(es): dc.creatorCuadrado Martin, Luis-
Autor(es): dc.creatorAlves Silva, Bruno-
Autor(es): dc.creatorGarcia Zanati Bazan, Silméia-
Autor(es): dc.creatorBarretti, Pasqual-
Autor(es): dc.creatorRegina Nogueira, Célia-
Data de aceite: dc.date.accessioned2025-08-21T21:36:35Z-
Data de disponibilização: dc.date.available2025-08-21T21:36:35Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1080/07420528.2023.2282471-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/304107-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/304107-
Descrição: dc.descriptionThe objective of this study was to assess the value of the abnormal circadian blood pressure pattern by ambulatory blood pressure monitoring (ABPM) to predict the onset of abnormal albuminuria in normotensive and normoalbuminuric DM1 patients. The participators were submitted to ABPM and followed prospectively until the onset of albuminuria or the end of follow-up. The patients with normal circadian blood pressure pattern were compared with the non-dippers in regard of the time interval free of albuminuria. The survival curves were evaluated by the Kaplan–Meier method. Of 34 patients screened, 10 patients matched the exclusion criteria. Therefore, 24 patients were submitted to ABPM, aged 24 ± 8.3 y, 18 men, and all Caucasian. Elevated levels of albuminuria did not occurin any individual with normal systolic blood pressure dip (>10%) at 54 months of follow-up. Only 22% of patients among non-dippers were free of albuminuria (<30 mg/g maintained for 3 months) at the same time (p = 0.049). Patients that reached the outcome were homogeneous in regard to other clinical and ABPM data evaluated. Abnormal systolic blood pressure circadian pattern predicts the evolution to incipient nephropathy in normotensive normoalbuminuric DM1 patients.-
Descrição: dc.descriptionNephrology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Descrição: dc.descriptionCardiology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Descrição: dc.descriptionEndocrinology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Descrição: dc.descriptionNephrology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Descrição: dc.descriptionCardiology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Descrição: dc.descriptionEndocrinology Discipline Department of Internal Medicine São Paulo State University (Unesp) Botucatu Medical School-
Formato: dc.format1523-1528-
Idioma: dc.languageen-
Relação: dc.relationChronobiology International-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAlbuminuria-
Palavras-chave: dc.subjectambulatory blood pressure monitoring-
Palavras-chave: dc.subjectblood pressure circadian rhythm-
Palavras-chave: dc.subjectdiabetes mellitus-
Palavras-chave: dc.subjectdiabetic nephropathy-
Título: dc.titleNon-dipping circadian pattern as a predictor of incipient nephropathy in normotensive normoalbuminuric type 1 diabetics-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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