Effects of quercetin on mineralized dental tissues: A scoping review

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Católica Portuguesa-
Autor(es): dc.contributorFaculty of Dental Medicine-
Autor(es): dc.contributorUniversidade Federal de Minas Gerais (UFMG)-
Autor(es): dc.contributorUniversity of Michigan-
Autor(es): dc.contributorUniversity Medical Center Göttingen-
Autor(es): dc.creatorNunes, Gabriel Pereira-
Autor(es): dc.creatorde Oliveira Alves, Renata-
Autor(es): dc.creatorRagghianti, Matheus Henrique Faccioli-
Autor(es): dc.creatordos Reis-Prado, Alexandre Henrique-
Autor(es): dc.creatorde Toledo, Priscila Toninatto Alves-
Autor(es): dc.creatorMartins, Tamires Passadori-
Autor(es): dc.creatorVieira, Ana Paula Miranda-
Autor(es): dc.creatorPeres, Geórgia Rondó-
Autor(es): dc.creatorDuque, Cristiane-
Data de aceite: dc.date.accessioned2025-08-21T17:52:49Z-
Data de disponibilização: dc.date.available2025-08-21T17:52:49Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.archoralbio.2024.106119-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/303961-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/303961-
Descrição: dc.descriptionObjective: This scoping review (SR) aimed to investigate the impact of quercetin on mineralized dental tissues intended to be used in preventive and restorative dentistry. Methods: This SR was conducted following the PRISMA-ScR statement. A comprehensive search was performed across databases for articles published up to March 2024. Eligible studies included in vitro and in situ studies and evaluating the potential therapeutic effects of quercetin on dental enamel and dentin. Data were extracted, and synthesis of study findings was conducted. Results: Out of the 2322 records screened, 22 studies were included in the review. Quercetin, in solution or into dental materials increased the bond strength to enamel and dentin. Additionally, quercetin also enhanced the bond strength of enamel after bleaching. Co-administration of quercetin with fluoride prevented erosive wear and inhibited the proteolytic activity in dentin more effectively than either agent alone. Hardness and modulus of elasticity was higher in dentin treated with quercetin compared to placebo. Reduction of nanoleakage at the composite-dentin interface was reduced in the presence of quercetin as a solution or incorporated into dental adhesives. Conclusions: Quercetin exhibits promising therapeutic effects on mineralized dental tissues, including remineralization and enhancement of bond strength. It shows potential as a multifunctional agent for improving the longevity and effectiveness of dental biomaterials, as well as in preventing erosion and dental caries. However, as these conclusions are largely drawn from lab-based (in vitro) studies, further research, including clinical trials, is needed to fully explore its therapeutic potential and applications in dentistry.-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Descrição: dc.descriptionFaculty of Dental Medicine Centre for Interdisciplinary Research in Health (CIIS) Universidade Católica Portuguesa-
Descrição: dc.descriptionLaboratory for Bone Metabolism and Regeneration University of Porto Faculty of Dental Medicine-
Descrição: dc.descriptionDepartment of Restorative Dentistry School of Dentistry Federal University of Minas Gerais (UFMG)-
Descrição: dc.descriptionDepartment of Cariology Restorative Sciences and Endodontics School of Dentistry University of Michigan-
Descrição: dc.descriptionDepartment of Preventive Dentistry Periodontology and Cariology University Medical Center Göttingen-
Descrição: dc.descriptionDepartment of Preventive and Restorative Dentistry Araçatuba School of Dentistry São Paulo State University - UNESP, SP-
Idioma: dc.languageen-
Relação: dc.relationArchives of Oral Biology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDental caries-
Palavras-chave: dc.subjectDentin-
Palavras-chave: dc.subjectEnamel-
Palavras-chave: dc.subjectPolyphenols-
Palavras-chave: dc.subjectTooth erosion-
Título: dc.titleEffects of quercetin on mineralized dental tissues: A scoping review-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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