Smart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorVellore Institute of Technology-
Autor(es): dc.contributorTerasaki Institute for Biomedical Innovation-
Autor(es): dc.contributorUniversity of Seoul-
Autor(es): dc.contributorUniversity of Colorado Boulder-
Autor(es): dc.contributorDuke University School of Medicine-
Autor(es): dc.contributorStanford University-
Autor(es): dc.contributorAmirkabir University of Technology (Tehran Polytechnic)-
Autor(es): dc.contributorCentral University of Gujarat-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorCalifornia State University-
Autor(es): dc.contributorGeorge Mason University-
Autor(es): dc.creatorRaheem, Ansheed-
Autor(es): dc.creatorMandal, Kalpana-
Autor(es): dc.creatorBiswas, Swarup-
Autor(es): dc.creatorAhari, Amir-
Autor(es): dc.creatorHassani Najafabadi, Alireza-
Autor(es): dc.creatorFarhadi, Neda-
Autor(es): dc.creatorZehtabi, Fatemeh-
Autor(es): dc.creatorGangrade, Ankit-
Autor(es): dc.creatorMecwan, Marvin-
Autor(es): dc.creatorMaity, Surjendu-
Autor(es): dc.creatorSharma, Saurabh-
Autor(es): dc.creatorArputharaj, Joseph Nathanael-
Autor(es): dc.creatorKhan, Pearlin Amaan-
Autor(es): dc.creatorUdduttula, Anjaneyulu-
Autor(es): dc.creatorKouchehbaghi, Negar Hosseinzadeh-
Autor(es): dc.creatorKhorsandi, Danial-
Autor(es): dc.creatorVasita, Rajesh-
Autor(es): dc.creatorHaghniaz, Reihaneh-
Autor(es): dc.creatorHerculano, Rondinelli Donizetti-
Autor(es): dc.creatorJohn, Johnson V.-
Autor(es): dc.creatorKim, Hyeok-
Autor(es): dc.creatorDokmeci, Mehmet Remzi-
Autor(es): dc.creatorPopat, Ketul C.-
Autor(es): dc.creatorZhu, Yangzhi-
Autor(es): dc.creatorManivasagam, Geetha-
Data de aceite: dc.date.accessioned2025-08-21T18:44:03Z-
Data de disponibilização: dc.date.available2025-08-21T18:44:03Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-03-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1063/5.0238817-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/303567-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/303567-
Descrição: dc.descriptionSmart biomaterials have significantly impacted human healthcare by advancing the development of medical devices designed to function within human tissue, mimicking the behavior of natural tissues. While the intelligence of biomaterials has evolved from inert to active over the past few decades, smart biomaterials take this a step further by making their surfaces or bulk respond based on interactions with surrounding tissues, imparting outcomes similar to natural tissue functions. This interaction with the surrounding tissue helps in creating stimuli-responsive biomaterials, which can be useful in tissue engineering, regenerative medicine, autonomous drug delivery, orthopedics, and much more. Traditionally, material engineering focused on refining the static properties of biomaterials to accommodate them within the body without evoking an immune response, which was a major obstacle to their unrestricted operation. This review highlights and explains various engineering approaches currently under research for developing stimuli-responsive biomaterials that tune their outcomes based on responses to bodily factors like temperature, pH, and ion concentration or external factors like magnetism, light, and conductivity. Applications in soft and hard tissue engineering, 4D printing, and scaffold design are also discussed. The advanced application of microfluidics, like organ-on-a-chip models, extensively benefits from the intrinsic smart properties of biomaterials, which are also discussed below. The review further elaborates on how smart biomaterial engineering could revolutionize biosensor applications, thereby improving patient care quality. We delineate the limitations and key challenges associated with biomaterials, providing insights into the path forward and outlining future directions for developing next-generation biomaterials that will facilitate clinical translation.-
Descrição: dc.descriptionWentworth Institute of Technology-
Descrição: dc.descriptionCentre for Biomaterials Cellular and Molecular Theranostics (CBCMT) Vellore Institute of Technology-
Descrição: dc.descriptionTerasaki Institute for Biomedical Innovation, 21100 Erwin St-
Descrição: dc.descriptionSchool of Electrical and Computer Engineering Center for Smart Sensor System of Seoul (CS4) University of Seoul, 163 Seoulsiripdaero, Dongdaemun-gu-
Descrição: dc.descriptionDepartment of Chemical and Biological Engineering University of Colorado Boulder-
Descrição: dc.descriptionDepartment of Orthopaedic Surgery Duke University School of Medicine, 203 Research Drive-
Descrição: dc.descriptionGeneral Surgery School of Medicine Stanford University, 300 Pasteur Drive-
Descrição: dc.descriptionDepartment of Textile Engineering Amirkabir University of Technology (Tehran Polytechnic), Hafez Avenue-
Descrição: dc.descriptionBiomaterials and Biomimetics Laboratory School of Life Sciences Central University of Gujarat, Gujarat-
Descrição: dc.descriptionBioengineering and Biomaterials Group São Paulo State University (UNESP) School of Pharmaceutical Sciences, SP-
Descrição: dc.descriptionAutonomy Research Center for STEAHM (ARCS) California State University-
Descrição: dc.descriptionDepartment of Bioengineering College of Engineering and Computing George Mason University, Suite 3100 Peterson Hall, 4400 University Drive, MS1J7-
Descrição: dc.descriptionSchool of Healthcare Science and Engineering (SHINE) Vellore Institute of Technology-
Descrição: dc.descriptionBioengineering and Biomaterials Group São Paulo State University (UNESP) School of Pharmaceutical Sciences, SP-
Idioma: dc.languageen-
Relação: dc.relationApplied Physics Reviews-
???dc.source???: dc.sourceScopus-
Título: dc.titleSmart biomaterials in healthcare: Breakthroughs in tissue engineering, immunomodulation, patient-specific therapies, and biosensor applications-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.