Fluid therapy and pulmonary complications in abdominal surgeries: randomized controlled trial

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.contributorand Pain Medicine-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorCastro, Gabriel Isaac Pereira de-
Autor(es): dc.creatorCastro, Renata Sayuri Ansai Pereira de-
Autor(es): dc.creatorLima, Rodrigo Moreira e-
Autor(es): dc.creatorSantos, Bruna Nogueira dos-
Autor(es): dc.creatorNavarro e Lima, Lais Helena-
Data de aceite: dc.date.accessioned2025-08-21T20:20:40Z-
Data de disponibilização: dc.date.available2025-08-21T20:20:40Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-07-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bjane.2024.844500-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/303339-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/303339-
Descrição: dc.descriptionBackground: There is no consensus on the most effective strategy for Postoperative Pulmonary Complication (PPC) reduction. This study hypothesized that a Goal-Directed Fluid Therapy (GDFT) protocol of infusion of predetermined boluses reduces the occurrence of PPC in patients undergoing elective open abdominal surgeries when compared with Standard of Care (SOC) strategy. Methods: Randomized, prospective, controlled study, conducted from May 2012 to December 2014, with ASA I, II or III patients undergoing open abdominal surgeries, lasting at least 120 min, under general anesthesia, randomized into the SOC and the GDFT group. In the SOC, fluid administration was according to the anesthesiologist's discretion. In the GDFT, the intervention protocol, based on bolus infusion according to blood pressure and delta pulse pressure, was applied. Patients were postoperatively evaluated by an anesthesiologist blinded to the group allocation regarding PPC incidence, mortality, and Length of Hospital Stay (LOHS). Results: Forty-two patients in the SOC group and 43 in the GDFT group. Nineteen patients (45%) in the SOC and 6 in the GDFT (14%) had at least one PPC (p = 0.003). There was no difference in mortality or LOHS between the groups. Among the patients with PPC, four died (25%), compared to two deaths in patients without PPC (3%) (p = 0.001). The LOHS had a median of 14.5 days in the group with PPC and 9 days in the group without PPC (p = 0.001). Conclusion: The GDFT protocol resulted in a lower rate of PPC; however, the LOHS and mortality did not reduce.-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu (FMB), SP-
Descrição: dc.descriptionUniversidade Federal de São Carlos (UFSCar), SP-
Descrição: dc.descriptionUniversity of Manitoba Department of Anesthesia Perioperative and Pain Medicine-
Descrição: dc.descriptionUniversidade de São Paulo (USP) Escola de Enfermagem de Ribeirão Preto, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu (FMB) Departamento de Anestesiologia e Especialidades Cirúrgicas Programa de Pós-Graduação, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu (FMB), SP-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Medicina de Botucatu (FMB) Departamento de Anestesiologia e Especialidades Cirúrgicas Programa de Pós-Graduação, SP-
Idioma: dc.languageen-
Relação: dc.relationBrazilian Journal of Anesthesiology (English Edition)-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAnesthesia-
Palavras-chave: dc.subjectDigestive system surgical procedures-
Palavras-chave: dc.subjectFluid therapy-
Palavras-chave: dc.subjectHemodynamic monitoring-
Palavras-chave: dc.subjectOrganism hydration status-
Palavras-chave: dc.subjectPostoperative complications-
Título: dc.titleFluid therapy and pulmonary complications in abdominal surgeries: randomized controlled trial-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.