Development of an Antioxidant, Anti-Aging, and Photoprotective Phytocosmetic from Discarded Agave sisalana Perrine Roots

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorSão Camilo University Center-
Autor(es): dc.contributorNossa Senhora do Patrocínio University Center (CEUNSP)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.creatorMazo, Guilherme dos Santos-
Autor(es): dc.creatorFracasso, Julia Amanda Rodrigues-
Autor(es): dc.creatorda Costa, Luísa Taynara Silvério-
Autor(es): dc.creatorFarias Ximenes, Valdecir-
Autor(es): dc.creatorZoppe, Natália Alves-
Autor(es): dc.creatorViel, Amanda Martins-
Autor(es): dc.creatorGuarnier, Lucas Pires-
Autor(es): dc.creatorSilva, Beatriz de Castro-
Autor(es): dc.creatorde Almeida, Luan Victor Coelho-
Autor(es): dc.creatordos Santos, Lucinéia-
Data de aceite: dc.date.accessioned2025-08-21T21:41:16Z-
Data de disponibilização: dc.date.available2025-08-21T21:41:16Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-06-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/cosmetics11030104-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/303247-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/303247-
Descrição: dc.descriptionThe primary source of hard fiber globally is Agave sisalana Perrine, also known as sisal. In areas where sisal is grown, the roots of the plant are usually left in the field after it has stopped producing, which leads to soil degradation and decreased sisal productivity. It is, therefore, critical to find alternatives to reuse this waste. This study explores the potential use of sisal waste in the cosmetic industry by incorporating a hydroethanolic extract (HER) into a cream–gel formulation, taking advantage of the plant’s recognized ethnopharmacological value. The study involves analyzing the extract’s phytochemical composition (flavonoids) and evaluating its cytotoxicity. Subsequently, the antioxidant and antiglycation activities of the extract and cream–gel are evaluated, as well as ex vivo ocular toxicity, photoprotective activity, and preliminary stability analyses. The HER extract showed a flavonoid composition (catechin, kaempferol, isorhamnetin, and chrysin) and maintained cell viability above 70% throughout all time points analyzed in the MTT assay. Furthermore, the extract and the formulation demonstrated proven antioxidant and antiglycation activities. The cream–gel’s UVB and UVA protection effectiveness with the HER was comparable to that of synthetic UVB/UVA sunscreens, with the samples proving nonirritating and stable. In conclusion, the extract has a significant presence of flavonoids, and the cream–gel developed with it did not present cytotoxicity and met the stability requirements, indicating phytocosmetic potential with antioxidant, antiglycation, and photoprotective properties.-
Descrição: dc.descriptionDepartment of Biotechnology School of Sciences and Languages São Paulo State University Dom Antonio Avenue, SP-
Descrição: dc.descriptionSchool of Dentistry São Paulo State University (UNESP), 1193, José Bonifacio Street-
Descrição: dc.descriptionDepartment of Chemistry Faculty of Sciences São Paulo State University (UNESP), SP-
Descrição: dc.descriptionSão Camilo University Center, SP-
Descrição: dc.descriptionNossa Senhora do Patrocínio University Center (CEUNSP), SP-
Descrição: dc.descriptionDepartment of Genetics Ribeirão Preto Medical School University of São Paulo, Ribeirão Preto, SP-
Descrição: dc.descriptionDepartment of Biotechnology School of Sciences and Languages São Paulo State University Dom Antonio Avenue, SP-
Descrição: dc.descriptionSchool of Dentistry São Paulo State University (UNESP), 1193, José Bonifacio Street-
Descrição: dc.descriptionDepartment of Chemistry Faculty of Sciences São Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationCosmetics-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectagave-
Palavras-chave: dc.subjectflavonoids-
Palavras-chave: dc.subjectphytocosmetic-
Título: dc.titleDevelopment of an Antioxidant, Anti-Aging, and Photoprotective Phytocosmetic from Discarded Agave sisalana Perrine Roots-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.