Strontium-loaded titanium surface promotes the MC3T3-E1 pre-osteoblasts growth and S. aureus adhesion

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorAir Force Hospital of Manaus (HAMN)-
Autor(es): dc.contributorFederal University of Rio Grande do Sul (UFRGS)-
Autor(es): dc.contributorUniversidade Federal de São Carlos (UFSCar)-
Autor(es): dc.creatorCominotte, Mariana Aline-
Autor(es): dc.creatorSantana, Luis Carlos Leal-
Autor(es): dc.creatorde Foggi, Camila Cristina-
Autor(es): dc.creatorMatos, Flavia Gomes-
Autor(es): dc.creatorFlorian, Fernanda-
Autor(es): dc.creatorde Assis, Marcelo-
Autor(es): dc.creatorVergani, Carlos Eduardo-
Autor(es): dc.creatorVaz, Luis Geraldo-
Autor(es): dc.creatorLongo, Elson-
Autor(es): dc.creatorCirelli, Joni Augusto-
Data de aceite: dc.date.accessioned2025-08-21T17:11:32Z-
Data de disponibilização: dc.date.available2025-08-21T17:11:32Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-04-28-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1557/s43578-024-01305-9-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/302910-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/302910-
Descrição: dc.descriptionAddressing the challenges of biomedical implant failures necessitates innovative approaches within biomaterials research. This study introduces a groundbreaking methodology to enhance both osteogenic and antibacterial properties in biomedical implants focusing on strontium properties. Three titanium surfaces—machine-polished (control), alkaline-etched (AES), and strontium-loaded alkaline-etched (Sr-AES) were evaluated. The results highlight the AES and Sr-AES groups exhibit heightened surface free energy and wettability. Sr+ release peaks on days 1 and 3, tapering off later timepoints. The Sr-AES group demonstrates a trend toward increased MC3T3-E1 proliferation at days 10 and 14. Notwithstanding, the AES and Sr-AES groups presented a greater proportion of viable S. aureus compared to the control. This study unveils Sr-AES as a novel titanium surface modification, showing potential in fostering MC3T3-E1 pre-osteoblast cell growth despite lacking antibiofilm effects. These findings bear significant implications for the progression of biomedical implants, urging sustained innovation in materials design for enhanced biological compatibility. Graphical abstract: (Figure presented.).-
Descrição: dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery UNESP School of Dentistry at Araraquara São Paulo State University, São Paulo-
Descrição: dc.descriptionDivision of Dentistry Air Force Hospital of Manaus (HAMN), Amazonas-
Descrição: dc.descriptionDepartment of Conservative Dentistry Dental School Federal University of Rio Grande do Sul (UFRGS), RS-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthesis UNESP School of Dentistry at Araraquara São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of Chemistry UFSCar Institute of Chemistry of São Carlos Federal University of São Carlos, São Paulo-
Descrição: dc.descriptionDepartment of Diagnosis and Surgery UNESP School of Dentistry at Araraquara São Paulo State University, São Paulo-
Descrição: dc.descriptionDepartment of Dental Materials and Prosthesis UNESP School of Dentistry at Araraquara São Paulo State University, São Paulo-
Descrição: dc.descriptionCAPES: 001-
Descrição: dc.descriptionFAPESP: 13/07296-2-
Formato: dc.format1232-1245-
Idioma: dc.languageen-
Relação: dc.relationJournal of Materials Research-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBiofilm-
Palavras-chave: dc.subjectBiomaterial-
Palavras-chave: dc.subjectOsteoblasts-
Palavras-chave: dc.subjectStrontium-
Palavras-chave: dc.subjectSurface chemistry-
Palavras-chave: dc.subjectTitanium-
Título: dc.titleStrontium-loaded titanium surface promotes the MC3T3-E1 pre-osteoblasts growth and S. aureus adhesion-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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