Identification, genotyping, and genomic comparison of Streptococcus porcinus isolated from diseased swine in Brazil

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorNerthus Research and Development LTDA-
Autor(es): dc.contributorEnvironmental Company of the State of São Paulo (CETESB)-
Autor(es): dc.creatorMatajira, Carlos E.C.-
Autor(es): dc.creatorMoreno, Luisa Z.-
Autor(es): dc.creatorPoor, Andre P.-
Autor(es): dc.creatorMonteiro, Matheus S.-
Autor(es): dc.creatorGomes, Vasco T.D.M.-
Autor(es): dc.creatorDutra, Maurício C.-
Autor(es): dc.creatorBarbosa, Mikaela R.F.-
Autor(es): dc.creatorSato, Maria I.Z.-
Autor(es): dc.creatorMoreno, Andrea M.-
Data de aceite: dc.date.accessioned2025-08-21T16:19:04Z-
Data de disponibilização: dc.date.available2025-08-21T16:19:04Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3855/jidc.19313-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/302633-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/302633-
Descrição: dc.descriptionIntroduction: Streptococcus porcinus is considered a zoonotic opportunistic pathogen for several animal species, including swine, and can cause systemic clinical conditions. There are morphological similarities between streptococcal species, leading to possible incorrect diagnosis and inappropriate treatment choice. Here, we describe the identification, and genotypic and genomic characterization of S. porcinus isolated from 5 adult sick pigs from Minas Gerais and São Paulo (Brazil) between 2010–2017. Methodology: Streptococcus spp. strains were isolated from vaginal discharge, joint abscess, and brain tissue received for routine diagnosis. They were identified as S. porcinus by mass spectrometry and partial sequencing of the groEL gene. Genotypic characterization by amplified fragment length polymorphism was performed. In addition, the genome of one of the S. porcinus invasive strains was sequenced and comparative analyses were performed. Results: Genotyping revealed that the nervous system and joint abscess invasive strains had higher genetic similarity and clustered separately from vaginal discharge strains. Genome sequencing of one of the invasive strains revealed the presence of genes conferring resistance to erythromycin, tetracycline, lincosamides, and macrolides. A high level of similarity of the Brazilian strain genome with British and American strains was found. However, these strains also presented higher variation in their accessory genomes. Conclusions: The circulation of S. porcinus invasive and resistant strains, and the lack of its identification demands attention, posing a risk for animals and workers in the swine industry.-
Descrição: dc.descriptionConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartment of Preventive Veterinary Medicine and Animal Health School of Veterinary Medicine and Animal Science University of São Paulo-
Descrição: dc.descriptionLaboratory of Microbial Biomolecules School of Pharmaceutical Sciences University of São Paulo-
Descrição: dc.descriptionDepartment of Pathology Reproduction and One Health School of Agricultural and Veterinarian Sciences São Paulo State University-
Descrição: dc.descriptionNerthus Research and Development LTDA-
Descrição: dc.descriptionEnvironmental Company of the State of São Paulo (CETESB)-
Descrição: dc.descriptionDepartment of Pathology Reproduction and One Health School of Agricultural and Veterinarian Sciences São Paulo State University-
Descrição: dc.descriptionCNPq: 154900/2018-4-
Descrição: dc.descriptionFAPESP: 2015/26159-1-
Descrição: dc.descriptionFAPESP: 2016/25745-7-
Descrição: dc.descriptionFAPESP: 2017/09515-4-
Descrição: dc.descriptionFAPESP: 2019/01192-7-
Descrição: dc.descriptionFAPESP: 2019/17683-0-
Descrição: dc.descriptionCNPq: 312684/2022-3-
Formato: dc.format1576-1582-
Idioma: dc.languageen-
Relação: dc.relationJournal of Infection in Developing Countries-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectgenotyping-
Palavras-chave: dc.subjectMALDI-TOF MS-
Palavras-chave: dc.subjectresistance-
Palavras-chave: dc.subjectStreptococcus porcinus-
Palavras-chave: dc.subjectswine-
Título: dc.titleIdentification, genotyping, and genomic comparison of Streptococcus porcinus isolated from diseased swine in Brazil-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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