Biocellulose-based hydrogel dressing as a strategy for the management of chronic arterial wounds

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorBiopolymers and Biomaterials Laboratory-
Autor(es): dc.creatorde Moraes, Carolina Magro Barreiros-
Autor(es): dc.creatorBassanelli, Arthur Mestriner-
Autor(es): dc.creatorRodrigues, Lenize da Silva-
Autor(es): dc.creatorBarud, Hernane da Silva-
Autor(es): dc.creatorFontes, Marina de Lima-
Autor(es): dc.creatorLourenção, Pedro Luiz Toledo de Arruda-
Autor(es): dc.creatorCastro, Meire Cristina Novelli E.-
Autor(es): dc.creatorBertanha, Matheus-
Data de aceite: dc.date.accessioned2025-08-21T22:41:52Z-
Data de disponibilização: dc.date.available2025-08-21T22:41:52Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/acb392924-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/302341-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/302341-
Descrição: dc.descriptionPurpose: To evaluate using a biocellulose-based hydrogel as an adjuvant in the healing process of arterial ulcers. Methods: A prospective single group quasi-experimental study was carried out with chronic lower limb arterial ulcer patients. These patients received biocellulose-based hydrogel dressings and outpatient guidance on dressing and periodic reassessments. The primary outcomes were the ulcer-healing rate and product safety, which were assessed by ulcer area measured in photographic records of pre-treatment and posttreatment after 7, 30, and 60 days. Secondary outcomes were related to clinical assessment by the quality-of-life scores (SF-36 and EQ-5D) and pain, evaluated by the visual analogue scale (VAS). Results: Seventeen participants were included, and one of them was excluded. Six patients (37%) had complete wound healing, and all patients had a significant reduction in the ulcer area during follow-up (233.6mm2 versus 2.7mm2) and reduction on the score PUSH 3.0 (p < 0.0001). The analysis of the SF-36 and EQ-5D questionnaires showed a statistically significant improvement in almost all parameters analyzed and with a reduction of pain assessed by the VAS. Conclusion: The biocellulose-based hydrogel was safe and showed a good perspective to promoting the necessary conditions to facilitate partial or complete healing of chronic arterial ulcers within a 60-day follow-up. Quality of life and pain were positively affected by the treatment.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionUniversidade Estadual Paulista – Hospital Clinics of the Faculty of Medicine of Botucatu-Department of Surgery and Orthopedics, SP-
Descrição: dc.descriptionCentro Universitário de Araraquara Biopolymers and Biomaterials Laboratory, SP-
Descrição: dc.descriptionUniversidade Estadual Paulista – Hospital Clinics of the Faculty of Medicine of Botucatu-Department of Surgery and Orthopedics, SP-
Descrição: dc.descriptionFAPESP: 2020/07761-0-
Idioma: dc.languageen-
Relação: dc.relationActa Cirurgica Brasileira-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAtherosclerosis-
Palavras-chave: dc.subjectPeripheral Arterial Disease-
Palavras-chave: dc.subjectWound Healing-
Palavras-chave: dc.subjectWounds and Injuries-
Título: dc.titleBiocellulose-based hydrogel dressing as a strategy for the management of chronic arterial wounds-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.