The impact of transformation zone representation on the frequency of abnormal cervical cytological results

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorBrazil-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorZago, Renata Alfena-
Autor(es): dc.creatorCamilo-Júnior, Deolino João-
Autor(es): dc.creatorPires D'Ávilla, Solange Correa Garcia-
Autor(es): dc.creatorXavier-Júnior, José Cândido Caldeira-
Data de aceite: dc.date.accessioned2025-08-21T20:55:27Z-
Data de disponibilização: dc.date.available2025-08-21T20:55:27Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-10-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ejogrb.2023.08.394-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/301753-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/301753-
Descrição: dc.descriptionObjective: To compare the frequency of abnormal cervical cytological results with and without representation of the transformation zone (TZ) in a medium-sized city in Brazil according to the Bethesda categorization. Methods: We performed an analytical observational study evaluating cytological results over 15 years from conventional smears collected within the Public Brazilian Health System in Araçatuba, Brazil. Tests were stratified by age and cytological result according to Brazilian guidelines and the Bethesda System. Results: There were 261,881 examinations, 159,251 with and 102,630 without TZ representation. The global frequency of abnormal results was higher in smears with TZ representation (crude odds ratio [OR] 4.03; 95% confidence interval [CI] [3.71–4.38]). Considering only women between 25 and 64 years (the target of the national guidelines), there were higher results for high-grade squamous intraepithelial lesions (OR 11.54; 95% CI 6.74–19.78), low-grade squamous intraepithelial lesions (OR 2.82; 95% CI 2.17–3.67) atypical squamous cell in which high-grade intraepithelial lesion cannot be excluded (OR 6.90; 95% CI 4.91–9.66) and atypical squamous cell of undetermined significance (OR 3.53; 95% CI 3.11–4.01) among cases with TZ representation. Conclusion: Samples with TZ representation were associated with higher rates of abnormal results. Health professionals should be regularly trained to understand the weakness of cytological examinations when the TZ is not represented, especially in developing countries.-
Descrição: dc.descriptionSchool of Medicine Centro Universitário Católico Unisalesiano Auxilium Araçatuba Brazil, Guatemala Street no. 414, São Paulo-
Descrição: dc.descriptionPathology Institute of Araçatuba São Paulo Brazil, Floriano Peixoto Street no. 808, São Paulo-
Descrição: dc.descriptionSão José do Rio Preto Medical School (FAMERP) São Paulo Brazil, Floriano Peixoto Street no. 808, São Paulo-
Descrição: dc.descriptionBotucatu Medical School Paulista State University Botucatu São Paulo Brazil, Floriano Peixoto Street no. 808, São Paulo-
Descrição: dc.descriptionBotucatu Medical School Paulista State University Botucatu São Paulo Brazil, Floriano Peixoto Street no. 808, São Paulo-
Formato: dc.format173-176-
Idioma: dc.languageen-
Relação: dc.relationEuropean Journal of Obstetrics and Gynecology and Reproductive Biology-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCytology-
Palavras-chave: dc.subjectEarly detection of cancer-
Palavras-chave: dc.subjectPapanicolaou test-
Palavras-chave: dc.subjectTransformation zone-
Palavras-chave: dc.subjectUterine cervical neoplasms-
Título: dc.titleThe impact of transformation zone representation on the frequency of abnormal cervical cytological results-
Tipo de arquivo: dc.typelivro digital-
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