Calcifying odontogenic cyst: A detailed international multicentric study

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual de Campinas (UNICAMP)-
Autor(es): dc.contributorUniversidade Federal do Rio de Janeiro (UFRJ)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidad Autónoma Metropolitana Xochimilco-
Autor(es): dc.contributorUniversidad de Chile (UChile)-
Autor(es): dc.contributorUniversidade Federal de Pernambuco (UFPE)-
Autor(es): dc.contributorUniversity of Pretoria (UP)-
Autor(es): dc.contributorPathCare Vermaak Histopathology Laboratory-
Autor(es): dc.creatorBezerra, Hélen Kaline Farias-
Autor(es): dc.creatorDutra, Mateus José-
Autor(es): dc.creatorRoza, Ana Luiza Oliveira Corrêa-
Autor(es): dc.creatorde Freitas, Stephanie Vargas-
Autor(es): dc.creatorKaminagakura, Estela-
Autor(es): dc.creatorAnbinder, Ana Lia-
Autor(es): dc.creatorVazquez-Garduño, Marcela-
Autor(es): dc.creatorRojas-Alcayaga, Gonzalo-
Autor(es): dc.creatorEspinoza-Santander, Iris Lucia-
Autor(es): dc.creatorPinto, Ana Verónica Ortega-
Autor(es): dc.creatorFarias, Danielle Machado-
Autor(es): dc.creatorCarvalho, Elaine Judite de Amorim-
Autor(es): dc.creatorde Castro, Jurema Freire Lisboa-
Autor(es): dc.creatorLopes, Márcio Ajudarte-
Autor(es): dc.creatorSantos-Silva, Alan Roger-
Autor(es): dc.creatorRobinson, Liam-
Autor(es): dc.creatorAbrahão, Aline Corrêa-
Autor(es): dc.creatorRomañach, Mário José-
Autor(es): dc.creatorvan Heerden, Willie-
Autor(es): dc.creatorMosqueda-Taylor, Adalberto-
Autor(es): dc.creatorVargas, Pablo Agustin-
Autor(es): dc.creatorPerez, Danyel Elias da Cruz-
Data de aceite: dc.date.accessioned2025-08-21T16:19:19Z-
Data de disponibilização: dc.date.available2025-08-21T16:19:19Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.oooo.2025.01.731-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/301726-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/301726-
Descrição: dc.descriptionObjective: To elucidate the histopathological, immunohistochemical, and ultrastructural characteristics of a large series of calcifying odontogenic cysts (COCs). Study Design: This was a multicenter cross-sectional retrospective study of seven oral pathology department laboratories from four countries. Clinical, demographic, and radiographic data of the patients were collected. Histopathological, immunohistochemical, and microstructural analyses were based on formalin-fixed, paraffin-embedded tissues. All variables were described, and associations were analyzed using Pearson's chi-square and Fisher's exact tests. Results: A total of 146 cases of COC were analyzed, including 141 central and 5 peripheral cases. Male patients were most involved, with a mean age of 27.8 years. The main clinical presentation was an asymptomatic swelling in the anterior maxilla. Radiographically, most cases appeared as a single well-defined unilocular radiolucency. Forty cases of COC were associated with other odontogenic lesions, including odontoma, ameloblastic fibroma, and odontogenic keratocyst. Immunohistochemical study showed cytoplasmic positivity for CK AE1/AE3, CK14, CK19, and Bcl-2 protein. Nuclear expression of β-catenin was observed in most cases. Conclusions: COC mainly affects adult males between the second and third decades of life. Asymptomatic maxillary swellings with diverse radiographic and histopathological presentations were noted. Moreover, COC may present associations with other odontogenic lesions, particularly odontomas in younger patients.-
Descrição: dc.descriptionDepartment of Oral Diagnosis Piracicaba Dental School University of Campinas (UNICAMP), São Paulo-
Descrição: dc.descriptionDepartment of Oral Diagnosis and Pathology School of Dentistry Federal University of Rio de Janeiro (UFRJ)-
Descrição: dc.descriptionInstitute of Science and Technology Department of Biosciences and Oral Diagnosis São Paulo State University (UNESP) São José dos Campos-
Descrição: dc.descriptionDepartamento de Atención a la Salud Universidad Autónoma Metropolitana Xochimilco-
Descrição: dc.descriptionOral Medicine and Pathology Department School of Dentistry Universidad de Chile (UChile)-
Descrição: dc.descriptionDepartment of Clinical and Preventive Dentistry Federal University of Pernambuco (UFPE), Pernambuco-
Descrição: dc.descriptionDepartment of Oral Pathology and Oral Biology School of Dentistry University of Pretoria (UP)-
Descrição: dc.descriptionDepartment of Oral and Maxillofacial Pathology School of Dentistry University of Pretoria (UP) Pretoria South Africa PathCare Vermaak Histopathology Laboratory-
Descrição: dc.descriptionInstitute of Science and Technology Department of Biosciences and Oral Diagnosis São Paulo State University (UNESP) São José dos Campos-
Idioma: dc.languageen-
Relação: dc.relationOral Surgery, Oral Medicine, Oral Pathology and Oral Radiology-
???dc.source???: dc.sourceScopus-
Título: dc.titleCalcifying odontogenic cyst: A detailed international multicentric study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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