Assessing the effect of β-glucan diets on innate immune response of tilapia macrophages against trichlorfon exposure: an in vitro study

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Autor(es): dc.contributorUniversidad de León-
Autor(es): dc.contributorUniversitat Autònoma de Barcelona-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.creatorFierro-Castro, Camino-
Autor(es): dc.creatorTort, Lluís-
Autor(es): dc.creatorMingatto, Fábio Erminio-
Autor(es): dc.creatorBiller, Jaqueline Dalbello-
Data de aceite: dc.date.accessioned2025-08-21T16:36:54Z-
Data de disponibilização: dc.date.available2025-08-21T16:36:54Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-04-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s10695-023-01283-5-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/301490-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/301490-
Descrição: dc.descriptionThe widespread use of pesticides in some areas where fish species such as tilapia are farmed may cause damage to the environment and affect commercial fish and therefore, human health. Water leaching with the pesticide trichlorfon, during the fumigation season in the field, can affect water quality in fish farms and consequently affect fish health. At the same time, the use of immunomodulatory compounds such as β-glucan supplied in the diet has become widespread in fish farms as it has been shown that improves the overall immune response. The present research examines the immunomodulatory impacts observed in macrophages of Nile tilapia (Oreochromis niloticus) after being fed a diet supplemented with β-glucan for 15 days, followed by their in vitro exposure to trichlorfon, an organophosphate pesticide, at concentrations of 100 and 500 µg mL−1 for 24 h. The results showed that β-glucan diet improved the viability of cells exposed to trichlorfon and their antioxidant capacity. However, β-glucan did not counteract the effects of the pesticide as for the ability to protect against bacterial infection. From the present results, it can be concluded that β-glucan feeding exerted a protective role against oxidative damage in cells, but it was not enough to reduce the deleterious effects of trichlorfon on the microbicidal capacity of macrophages exposed to this pesticide.-
Descrição: dc.descriptionUniversidad de León-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionDepartamento de Biología Molecular Área de Genética Facultad de Ciencias Biológicas y Ambientales Universidad de León-
Descrição: dc.descriptionDepartmento de Biología Celular Fisiología E Inmunología Fac. Biociencas Universitat Autònoma de Barcelona-
Descrição: dc.descriptionDepartment of Animal Science College of Agricultural and Technological Sciences São Paulo State University (Unesp)-
Descrição: dc.descriptionDepartment of Animal Science College of Agricultural and Technological Sciences São Paulo State University (Unesp)-
Descrição: dc.descriptionFAPESP: Process number 2012/22016-3-
Formato: dc.format527-541-
Idioma: dc.languageen-
Relação: dc.relationFish Physiology and Biochemistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAquatic contaminants-
Palavras-chave: dc.subjectImmunomodulation-
Palavras-chave: dc.subjectInnate immunity-
Palavras-chave: dc.subjectMacrophages-
Palavras-chave: dc.subjectOreochromis niloticus-
Palavras-chave: dc.subjectOrganophosphates-
Palavras-chave: dc.subjectTrichlorfon-
Título: dc.titleAssessing the effect of β-glucan diets on innate immune response of tilapia macrophages against trichlorfon exposure: an in vitro study-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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