Doping dependency of chitosan and PAA controlled CdSe quantum dots for catalytic and bactericidal behavior by inhibiting DNA gyrase and DHFR through molecular docking

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MetadadosDescriçãoIdioma
Autor(es): dc.contributorGovernment College University Lahore-
Autor(es): dc.contributorUniversity of Agriculture-
Autor(es): dc.contributorUniversity of Management and Technology-
Autor(es): dc.contributorKing Fahd University of Petroleum & Minerals-
Autor(es): dc.contributorPINSTECH-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorNorthern Border university-
Autor(es): dc.creatorHassan, Mudassir-
Autor(es): dc.creatorIkram, Muhammad-
Autor(es): dc.creatorHaider, Ali-
Autor(es): dc.creatorShahzadi, Iram-
Autor(es): dc.creatorMoeen, Sawaira-
Autor(es): dc.creatorUl-Hamid, Anwar-
Autor(es): dc.creatorAli, Ghafar-
Autor(es): dc.creatorUllah, Hameed-
Autor(es): dc.creatorEbaid, Manal S.-
Autor(es): dc.creatorGraeff, Carlos F.O.-
Data de aceite: dc.date.accessioned2025-08-21T19:14:46Z-
Data de disponibilização: dc.date.available2025-08-21T19:14:46Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-01-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ijbiomac.2024.138690-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/301316-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/301316-
Descrição: dc.descriptionThe presence of toxic dyes in industrial waste dramatically diminishes the beneficial effects of remediation efforts. To overcome the hazardous impacts of dyes on biodiversity and environment, we integrated polymers into nanoparticles to substantially enhance their functionality and performance. 2 and 4 wt% of chitosan (CS) and 3 wt% of polyacrylic acid (PAA) doped cadmium selenide (CdSe) nanostructures (NSs) were prepared by co-precipitation approach. CdSe quantum dots (QDs) exhibit a narrow band gap energy, high solubility, and tunable properties, which are appropriate for redox reactions but show less adsorption and catalytic behavior. In this work, catalytic and antibacterial activities of CdSe QDs enhanced upon the integration of PAA due to increment in surface area confirmed by BET analysis. Furthermore, the addition of CS escalates the dye degradation and microbes evolve to the interaction of CdSe surface with the functional groups of CS. Highly doped CdSe shows significant inhibitory zones (8.65 to 9.30 mm) against gram-positive bacteria Staphylococcus aureus (S. aureus). In addition, the inhibitory activity of CS/PAA-CdSe nanostructures against DNA gyrase and dihydrofolate reductase (DHFR) in S. aureus was elucidated using molecular docking investigations, providing a rationale for their bactericidal action.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionNorthern Border University-
Descrição: dc.descriptionSolar Cell Applications Research Lab Department of Physics Government College University Lahore, Punjab-
Descrição: dc.descriptionDepartment of Clinical Medicine Faculty of Veterinary and Animal Sciences Muhammad Nawaz Shareef University of Agriculture, Punjab-
Descrição: dc.descriptionSchool of Pharmacy University of Management and Technology-
Descrição: dc.descriptionCore Research Facilities King Fahd University of Petroleum & Minerals-
Descrição: dc.descriptionNanomaterials Research Group (NRG) Physics Division PINSTECH-
Descrição: dc.descriptionDepartment of Physics and Meteorology School of Sciences Sao Paulo State University (UNESP), Bauru-
Descrição: dc.descriptionDepartment of Chemistry College of Science Northern Border university-
Descrição: dc.descriptionDepartment of Physics and Meteorology School of Sciences Sao Paulo State University (UNESP), Bauru-
Descrição: dc.descriptionFAPESP: 2020/12356-8-
Descrição: dc.descriptionFAPESP: 2024/02264-0-
Descrição: dc.descriptionFAPESP: CNPq INCT/NanoVida-
Descrição: dc.descriptionNorthern Border University: NBU- FPEJ-2024-80-02-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Biological Macromolecules-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectCdSe-
Palavras-chave: dc.subjectChitosan-
Palavras-chave: dc.subjectRhB degradation-
Título: dc.titleDoping dependency of chitosan and PAA controlled CdSe quantum dots for catalytic and bactericidal behavior by inhibiting DNA gyrase and DHFR through molecular docking-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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