Global anaesthesia-related cardiac arrest rates in children: a systematic review and meta-analysis

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorGeneral Intensive Care Unit of the Shaare Zedek Medical Centre-
Autor(es): dc.contributorHebrew University Faculty of Medicine-
Autor(es): dc.creatorTiradentes, Teofilo Augusto A.-
Autor(es): dc.creatorEinav, Sharon-
Autor(es): dc.creatorBraz, Jose R.C.-
Autor(es): dc.creatorNunes-Nogueira, Vania S.-
Autor(es): dc.creatorBetini, Marluci-
Autor(es): dc.creatorCorrente, Jose E.-
Autor(es): dc.creatorBraz, Mariana G.-
Autor(es): dc.creatorBraz, Leandro G.-
Data de aceite: dc.date.accessioned2025-08-21T22:09:58Z-
Data de disponibilização: dc.date.available2025-08-21T22:09:58Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-10-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.bja.2023.08.023-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/300851-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/300851-
Descrição: dc.descriptionBackground: Neonates and infants have a higher perioperative risk of cardiac arrest and mortality than adults. The Human Development Index (HDI) ranges from 0 to 1, representing the lowest and highest levels of development, respectively. The relation between anaesthesia safety and country HDI has been described previously. We examined the relationship among the anaesthesia-related cardiac arrest rate (ARCAR), country HDI, and time in a mixed paediatric patient population. Methods: Electronic databases were searched up to July 2022 for studies reporting 24-h postoperative ARCARs in children. ARCARs (per 10,000 anaesthetic procedures) were analysed in low-HDI (HDI<0.8) vs high-HDI countries (HDI≥0.8) and over time (pre-2001 vs 2001–22). The magnitude of these associations was studied using systematic review methods with meta-regression analysis and meta-analysis. Results: We included 38 studies with 5,493,489 anaesthetic procedures and 1001 anaesthesia-related cardiac arrests. ARCARs were inversely correlated with country HDI (P<0.0001) but were not correlated with time (P=0.82). ARCARs did not change between the periods in either high-HDI or low-HDI countries (P=0.71 and P=0.62, respectively), but were higher in low-HDI countries than in high-HDI countries (9.6 vs 2.0; P<0.0001) in 2001–22. ARCARs were higher in children aged <1 yr than in those ≥1 yr in high-HDI (10.69 vs 1.48; odds ratio [OR] 8.03, 95% confidence interval [CI] 5.96–10.81; P<0.0001) and low-HDI countries (36.02 vs 2.86; OR 7.32, 95% CI 3.48–15.39; P<0.0001) in 2001–22. Conclusions: The high and alarming anaesthesia-related cardiac arrest rates among children younger than 1 yr of age in high-HDI and low-HDI countries, respectively, reflect an ongoing challenge for anaesthesiologists. Systematic review protocol: PROSPERO CRD42021229919.-
Descrição: dc.descriptionAnaesthesia Cardiac Arrest and Mortality Study Commission Department of Surgical Specialties and Anaesthesiology Botucatu Medical School Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionGeneral Intensive Care Unit of the Shaare Zedek Medical Centre-
Descrição: dc.descriptionHebrew University Faculty of Medicine-
Descrição: dc.descriptionDepartment of Internal Medicine Botucatu Medical School Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionTechnical Division of Library and Documentation Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Biosciences Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionAnaesthesia Cardiac Arrest and Mortality Study Commission Department of Surgical Specialties and Anaesthesiology Botucatu Medical School Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionDepartment of Internal Medicine Botucatu Medical School Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionTechnical Division of Library and Documentation Sao Paulo State University - UNESP, Sao Paulo-
Descrição: dc.descriptionDepartment of Biostatistics Institute of Biosciences Sao Paulo State University - UNESP, Sao Paulo-
Formato: dc.format901-913-
Idioma: dc.languageen-
Relação: dc.relationBritish Journal of Anaesthesia-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectcardiac arrest-
Palavras-chave: dc.subjectchildren-
Palavras-chave: dc.subjectdeveloped countries-
Palavras-chave: dc.subjectdeveloping countries-
Palavras-chave: dc.subjectsystematic review-
Título: dc.titleGlobal anaesthesia-related cardiac arrest rates in children: a systematic review and meta-analysis-
Tipo de arquivo: dc.typevídeo-
Aparece nas coleções:Repositório Institucional - Unesp

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