Effect of fluoride gels with nanosized sodium trimetaphosphate on the in vitro remineralization of caries lesions

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Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorPrograma de Pós-graduação em Ciências da Saúde-
Autor(es): dc.contributorPeriodontology and Cariology-
Autor(es): dc.creatorNagata, Mariana Emi-
Autor(es): dc.creatorDelbem, Alberto Carlos Botazzo-
Autor(es): dc.creatorBáez-Quintero, Liliana Carolina-
Autor(es): dc.creatorDanelon, Marcelle-
Autor(es): dc.creatorSampaio, Caio-
Autor(es): dc.creatorMonteiro, Douglas Roberto-
Autor(es): dc.creatorWiegand, Annette-
Autor(es): dc.creatorPessan, Juliano Pelim-
Data de aceite: dc.date.accessioned2025-08-21T17:06:03Z-
Data de disponibilização: dc.date.available2025-08-21T17:06:03Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2022-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1590/1678-7757-2023-0115-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/300777-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/300777-
Descrição: dc.descriptionObjective: To evaluate the effects of fluoride (F) gels supplemented with micrometric or nano-sized sodium trimetaphosphate (TMPmicro and TMPnano, respectively) on the in vitro remineralization of caries-like lesions. Methodology: Bovine enamel subsurface lesions (n=168) were selected according to their surface hardness (SH) and randomly divided into seven groups (n=24/group): Placebo (without F/TMP), 4,500 ppm F (4500F), 4500F + 2.5% TMPnano (2.5% Nano), 4500F + 5% TMPnano (5% Nano), 4500F + 5% TMPmicro (5% Micro), 9,000 ppm F (9000F), and 12,300 ppm F (Acid gel). The gels were applied in a thin layer for one minute. Half of the blocks were subjected to pH cycling for six days, whereas the remaining specimens were used for loosely-(calcium fluoride; CaF2) and firmly-bound (fluorapatite; FA) fluoride analysis. The percentage of surface hardness recovery (%SHR), area of subsurface lesion (ΔKHN), CaF2, FA, calcium (Ca), and phosphorus (P) on/in enamel were determined. Data (log10-transformed) were subjected to ANOVA and the Student-Newman-Keuls’ test (p<0.05). Results: We observed a dose-response relation between F concentrations in the gels without TMP for %SHR and ΔKHN. The 2.5% Nano and 5% Micro reached similar %SHR when compared with 9000F and Acid gels. For ΔKHN, Placebo and 5% Nano gels had the highest values, and 5% Micro, 2.5% Nano, 9000F, and Acid gels, the lowest. All groups had similar retained CaF2 values, except for Placebo and Acid gel. We verified observed an increase in Ca concentrations in nano-sized TMP groups. Regarding P, TMP groups showed similar formation and retention to 9000F and Acid. Conclusion: Adding 2.5% nano-sized or 5% micrometric TMP to low-fluoride gels lead to enhanced in vitro remineralization of artificial caries lesions.-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Odontologia-Araçatuba Departamento de Odontologia Preventiva e Restauradora-Rua José Bonifacio, SP-
Descrição: dc.descriptionUniversidade do Oeste Paulista (UNOESTE) Programa de Pós-graduação em Ciências da Saúde, Presidente Prudente-
Descrição: dc.descriptionUniversity Medical Center Göttingen Department of Preventive Dentistry Periodontology and Cariology-
Descrição: dc.descriptionUniversidade Estadual Paulista (UNESP) Faculdade de Odontologia-Araçatuba Departamento de Odontologia Preventiva e Restauradora-Rua José Bonifacio, SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Applied Oral Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectDental Enamel-
Palavras-chave: dc.subjectFluorides-
Palavras-chave: dc.subjectNanoparticles-
Palavras-chave: dc.subjectNanotechnology-
Palavras-chave: dc.subjectPhosphates-
Título: dc.titleEffect of fluoride gels with nanosized sodium trimetaphosphate on the in vitro remineralization of caries lesions-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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