Microbial astaxanthin-encapsulated polymeric micelles from yeast Phaffia rhodozyma for personalized bioactive colored natural rubber latex bandages

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Autor(es): dc.contributorPontificia Universidad Católica de Valparaíso-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversity of Messina-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorTerasaki Institute for Biomedical Innovation (TIBI)-
Autor(es): dc.creatorMussagy, Cassamo U.-
Autor(es): dc.creatorDias, Júlia N.-
Autor(es): dc.creatorCaicedo-Paz, Angie V.-
Autor(es): dc.creatorGini, Ana L.R.-
Autor(es): dc.creatorScarim, Cauê B.-
Autor(es): dc.creatorTropea, Alessia-
Autor(es): dc.creatorLa Tella, Roberta-
Autor(es): dc.creatorMondello, Luigi-
Autor(es): dc.creatorLopes-Filho, Paulo E.L.-
Autor(es): dc.creatorTanaka, Jean L.-
Autor(es): dc.creatorPiazza, Rodolfo D.-
Autor(es): dc.creatorMarques, Rodrigo F.C.-
Autor(es): dc.creatorSantos, Lindomar S.-
Autor(es): dc.creatorLuiz, Marcela T.-
Autor(es): dc.creatorChorilli, Marlus-
Autor(es): dc.creatorSantos-Ebinuma, Valéria C.-
Autor(es): dc.creatorPessoa, Adalberto-
Autor(es): dc.creatorHerculano, Rondinelli D.-
Data de aceite: dc.date.accessioned2025-08-21T20:46:24Z-
Data de disponibilização: dc.date.available2025-08-21T20:46:24Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2025-05-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1016/j.ijbiomac.2025.141078-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/300691-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/300691-
Descrição: dc.descriptionThis study explores the development of bioactive, colored natural rubber latex (NRL) bandages by incorporating astaxanthin (AXT), a carotenoid with potent antioxidant and anti-inflammatory properties. AXT is produced by the yeast Phaffia rhodozyma under various light conditions to improve AXT biosynthesis and encapsulated in polymeric micelles to enhance its solubility and stability. The encapsulated AXT is then integrated into NRL bandages, imparting a orange-red hue and potentially therapeutic benefits. Physicochemical characterizations, including UV–Vis spectroscopy and FTIR, reveal interactions between AXT and the micelle components. The bandages exhibit improved hydrophilicity and maintain their thermal stability post-AXT incorporation. Antioxidant capacity assessments show that the NRL bandages retain a significant portion of AXT's antioxidant properties, which can aid in wound healing. The release profile of AXT from the bandages demonstrates an initial burst followed by sustained release, indicating effective delivery of the carotenoid. This innovative approach combines aesthetic appeal with biomedical advantages, offering a personalized solution for wound care applications.-
Descrição: dc.descriptionFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)-
Descrição: dc.descriptionEscuela de Agronomía Facultad de Ciencias Agronómicas y de los Alimentos Pontificia Universidad Católica de Valparaíso-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocesses and Biotechnology, SP-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Drugs and Medicines, SP-
Descrição: dc.descriptionMessina Institute of Technology c/o Department of Chemical Biological Pharmaceutical and Environmental Sciences former Veterinary School University of Messina, Viale G. Palatucci snc-
Descrição: dc.descriptionChromaleont s.r.l. c/o Department of Chemical Biological Pharmaceutical and Environmental Sciences University of Messina, viale Annunziata-
Descrição: dc.descriptionBioengineering & Biomaterials Group São Paulo State University (UNESP) School of Pharmaceutical Sciences, SP-
Descrição: dc.descriptionLaboratory of Magnetic Materials and Colloids Department of Analytical Chemistry Physical Chemistry and Inorganic Institute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionFaculty of Philosophy Sciences and Languages of Ribeirão Preto University of São Paulo (USP), 3900 Bandeirantes Avenue, SP-
Descrição: dc.descriptionDepartment of Pharmaceutical-Biochemical Technology School of Pharmaceutical Sciences University of São Paulo-
Descrição: dc.descriptionTerasaki Institute for Biomedical Innovation (TIBI), 11507 W Olympic Blvd-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Bioprocesses and Biotechnology, SP-
Descrição: dc.descriptionSão Paulo State University (UNESP) School of Pharmaceutical Sciences Department of Drugs and Medicines, SP-
Descrição: dc.descriptionBioengineering & Biomaterials Group São Paulo State University (UNESP) School of Pharmaceutical Sciences, SP-
Descrição: dc.descriptionLaboratory of Magnetic Materials and Colloids Department of Analytical Chemistry Physical Chemistry and Inorganic Institute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionFAPESP: 2015/11759–3-
Descrição: dc.descriptionFAPESP: 2021/06686–8-
Descrição: dc.descriptionFAPESP: 2023/17448–6-
Idioma: dc.languageen-
Relação: dc.relationInternational Journal of Biological Macromolecules-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAstaxanthin-
Palavras-chave: dc.subjectBandages-
Palavras-chave: dc.subjectBiocompatibility-
Palavras-chave: dc.subjectColoring-
Palavras-chave: dc.subjectNatural rubber latex-
Palavras-chave: dc.subjectPhaffia rhodozyma-
Palavras-chave: dc.subjectPolymeric micelles-
Título: dc.titleMicrobial astaxanthin-encapsulated polymeric micelles from yeast Phaffia rhodozyma for personalized bioactive colored natural rubber latex bandages-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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