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Metadados | Descrição | Idioma |
---|---|---|
Autor(es): dc.contributor | Universidade Estadual Paulista (UNESP) | - |
Autor(es): dc.contributor | José Bahia Sapucaia Private Clinic | - |
Autor(es): dc.creator | Rego, Rebeca Mayara Padilha | - |
Autor(es): dc.creator | Machado, Nilton Carlos | - |
Autor(es): dc.creator | Carvalho, Mary de Assis | - |
Autor(es): dc.creator | Graffunder, Johann Souza | - |
Autor(es): dc.creator | Fraguas, Crhistiano | - |
Autor(es): dc.creator | Ortolan, Erika Veruska Paiva | - |
Autor(es): dc.creator | Lourenção, Pedro Luiz Toledo de Arruda | - |
Data de aceite: dc.date.accessioned | 2025-08-21T16:04:56Z | - |
Data de disponibilização: dc.date.available | 2025-08-21T16:04:56Z | - |
Data de envio: dc.date.issued | 2025-04-29 | - |
Data de envio: dc.date.issued | 2023-12-31 | - |
Fonte completa do material: dc.identifier | http://dx.doi.org/10.3390/biomedicines12010164 | - |
Fonte completa do material: dc.identifier | https://hdl.handle.net/11449/300592 | - |
Fonte: dc.identifier.uri | http://educapes.capes.gov.br/handle/11449/300592 | - |
Descrição: dc.description | Background: Functional constipation can lead to painful defecations, fecal incontinence, and abdominal pain, significantly affecting a child’s quality of life. Treatment options include non-pharmacological and pharmacological approaches, but some cases are intractable and require alternative interventions like neuromodulation. A subtype of neuromodulation, called Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS), comprises electrical stimulation at the ankle level, by means of electrodes fixed to the skin. TPTNS is a minimally invasive, easy-to-apply technique that can potentially improve constipation symptoms in the pediatric population by stimulating the sacral nerves. Aim: To evaluate the clinical results and applicability of TPTNS as an adjuvant treatment for children and adolescents with functional constipation. Methods: Between April 2019 and October 2021, 36 patients diagnosed with functional constipation according to the Rome IV Criteria were invited to participate in the study. The study followed a single-center, uncontrolled, prospective cohort design. Patients received TPTNS for 4 or 8 weeks, with assessments conducted immediately after the periods of TPTNS and 4 weeks after the end of the intervention period. The data normality distribution was determined by the Shapiro–Wilk test. The Wilcoxon test and Student’s t-test for paired samples were used to compare quantitative variables, and the McNemar test was used to compare categorical variables. Results: Of the 36 enrolled patients, 28 children and adolescents with intractable function constipation completed the study, receiving TPTNS for 4 weeks. Sixteen patients (57.1%) extended the intervention period for 4 extra weeks, receiving 8 weeks of intervention. TPTNS led to significant improvements in stool consistency, frequency of defecation, and bowel function scores, with a reduction in abdominal pain. Quality of life across physical and psychosocial domains showed substantial enhancements. The quality of life-related to bowel habits also improved significantly, particularly in lifestyle, behavior, and embarrassment domains. The positive effects of this intervention are seen relatively early, detected after 4 weeks of intervention, and even 4 weeks after the end of the intervention. TPTNS was well-tolerated, with an adherence rate of approximately 78%, and no adverse effects were reported. Conclusions: TPTNS is an adjuvant treatment for intractable functional constipation, improving bowel function and quality of life. The effects of TPTNS were observed relatively early and sustained even after treatment cessation. | - |
Descrição: dc.description | Department of Surgery and Orthopedics Division of Pediatric Surgery Botucatu Medical School São Paulo State University (UNESP), SP | - |
Descrição: dc.description | Department of Pediatrics Division of Pediatric Gastroenterology Hepatology and Nutrition Botucatu Medical School São Paulo State University (UNESP), SP | - |
Descrição: dc.description | Botucatu Medical School São Paulo State University (UNESP), SP | - |
Descrição: dc.description | José Bahia Sapucaia Private Clinic, Salvador 41830-492, BA | - |
Descrição: dc.description | Department of Surgery and Orthopedics Division of Pediatric Surgery Botucatu Medical School São Paulo State University (UNESP), SP | - |
Descrição: dc.description | Department of Pediatrics Division of Pediatric Gastroenterology Hepatology and Nutrition Botucatu Medical School São Paulo State University (UNESP), SP | - |
Descrição: dc.description | Botucatu Medical School São Paulo State University (UNESP), SP | - |
Idioma: dc.language | en | - |
Relação: dc.relation | Biomedicines | - |
???dc.source???: dc.source | Scopus | - |
Palavras-chave: dc.subject | adolescent | - |
Palavras-chave: dc.subject | child | - |
Palavras-chave: dc.subject | constipation | - |
Palavras-chave: dc.subject | transcutaneous electric nerve stimulation | - |
Título: dc.title | Transcutaneous Posterior Tibial Nerve Stimulation: An Adjuvant Treatment for Intractable Constipation in Children | - |
Tipo de arquivo: dc.type | livro digital | - |
Aparece nas coleções: | Repositório Institucional - Unesp |
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