Heritability estimates and genome-wide association study of methane emission traits in Nellore cattle

Registro completo de metadados
MetadadosDescriçãoIdioma
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorFundación Universitaria Agraria de Colombia-UNIAGRARIA-
Autor(es): dc.contributorBeef Cattle Research Center-
Autor(es): dc.contributorEmpresa Brasileira de Pesquisa Agropecuária (EMBRAPA)-
Autor(es): dc.contributorNational Council for Science and Technological Development-
Autor(es): dc.creatorSouza, Luana Lelis-
Autor(es): dc.creatorDominguez-Castaño, Pablo-
Autor(es): dc.creatorGianvecchio, Sarah Bernardes-
Autor(es): dc.creatorSakamoto, Leandro Sannomiya-
Autor(es): dc.creatorRodrigues, Gustavo Roberto Dias-
Autor(es): dc.creatorda Silva Soares, Tainara Luana-
Autor(es): dc.creatorBonilha, Sarah Figueiredo Martins-
Autor(es): dc.creatorde Oliveira Santos Marcatto, Juliana-
Autor(es): dc.creatorAlbuquerque, Lucia Galvão-
Autor(es): dc.creatorVasconcelos Silva, Josineudson Augusto-
Autor(es): dc.creatorMercadante, Maria Eugênia Zerlotti-
Data de aceite: dc.date.accessioned2025-08-21T22:42:20Z-
Data de disponibilização: dc.date.available2025-08-21T22:42:20Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1093/jas/skae182-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/300152-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/300152-
Descrição: dc.descriptionThe objectives of the present study were to estimate the heritability for daily methane emission (CH4) and residual daily methane emission (CH4res) in Nellore cattle, as well as to perform genome-wide association studies (GWAS) to identify genomic regions and candidate genes influencing the genetic variation of CH4 and CH4res. Methane emission phenotypes of 743 Nellore animals belonging to 3 breeding programs were evaluated. CH4 was measured using the sulfur hexafluoride (SF6) tracer technique (which involves an SF6 permeation tube introduced into the rumen, and an appropriate apparatus on each animal), and CH4res was obtained as the difference between observed CH4 and CH4 adjusted for dry matter intake. A total of 6, 252 genotyped individuals were used for genomic analyses. Data were analyzed with a univariate animal model by the single-step GBLUP method using the average information restricted maximum likelihood (AIREML) algorithm. The effects of single nucleotide polymorphisms (SNPs) were obtained using a single-step GWAS approach. Candidate genes were identified based on genomic windows associated with quantitative trait loci (QTLs) related to the 2 traits. Annotation of QTLs and identification of candidate genes were based on the initial and final coordinates of each genomic window considering the bovine genome ARS-UCD1.2 assembly. Heritability estimates were of moderate to high magnitude, being 0.42 ± 0.09 for CH4 and 0.21 ± 0.09 for CH4res, indicating that these traits will respond rapidly to genetic selection. GWAS revealed 11 and 15 SNPs that were significantly associated (P < 10−6) with genetic variation of CH4 and CH4res, respectively. QTLs associated with feed efficiency, residual feed intake, body weight, and height overlapped with significant markers for the traits evaluated. Ten candidate genes were present in the regions of significant SNPs; 3 were associated with CH4 and 7 with CH4res. The identified genes are related to different functions such as modulation of the rumen microbiota, fatty acid production, and lipid metabolism. CH4 and CH4res presented sufficient genetic variation and may respond rapidly to selection. Therefore, these traits can be included in animal breeding programs aimed at reducing enteric methane emissions across generations.-
Descrição: dc.descriptionFaculty of Agricultural and Veterinarian Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionFacultad de Ciencias Agrarias Fundación Universitaria Agraria de Colombia-UNIAGRARIA-
Descrição: dc.descriptionInstitute of Animal Science (IZ) Beef Cattle Research Center-
Descrição: dc.descriptionEmbrapa Environment-
Descrição: dc.descriptionFaculty of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Descrição: dc.descriptionNational Council for Science and Technological Development-
Descrição: dc.descriptionFaculty of Agricultural and Veterinarian Sciences São Paulo State University (UNESP)-
Descrição: dc.descriptionFaculty of Veterinary Medicine and Animal Science São Paulo State University (UNESP)-
Idioma: dc.languageen-
Relação: dc.relationJournal of Animal Science-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectBos indicus-
Palavras-chave: dc.subjectgenes-
Palavras-chave: dc.subjectgenetic variance-
Palavras-chave: dc.subjectQTLs-
Título: dc.titleHeritability estimates and genome-wide association study of methane emission traits in Nellore cattle-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

Não existem arquivos associados a este item.