Association of asparagine in saliva with a lower risk of early childhood caries in undernourished children: a cross-sectional study

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Autor(es): dc.contributorUFC-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUT Health School of Dentistry-
Autor(es): dc.creatorLima, P. H.M.-
Autor(es): dc.creatorMota, A. C.M.-
Autor(es): dc.creatorLima, V.-
Autor(es): dc.creatorCidrao, G. P.-
Autor(es): dc.creatorToyama, D. O.-
Autor(es): dc.creatorToyama, M. H.-
Autor(es): dc.creatorFonteles, C. S.-
Data de aceite: dc.date.accessioned2025-08-21T23:23:32Z-
Data de disponibilização: dc.date.available2025-08-21T23:23:32Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2024-12-31-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.1007/s40368-025-01005-w-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/299769-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/299769-
Descrição: dc.descriptionAim: The aim was to investigate the salivary amino acid profile in children with protein-energy undernutrition (PEU) and its association with caries experience in the presence of other risk factors. Methods: The study had a cross-sectional design and was carried out with 122 children (12–71 months old), classified according to their level of undernutrition (mild—GI, n = 22; moderate—GII, n = 53) or healthy controls (GC, n = 47). The children were categorized based on the presence of caries into caries-experienced groups (ceos > 0, 22 CG, 12 GI and 18 GII) and caries-free groups (ceos = 0, 25 CG, 10 GI and 36 GII). Total unstimulated and stimulated saliva were collected to determine amino acids and Streptococcus mutans, respectively. Results: Eighteen amino acids were associated with PEU. Undernutrition and caries experience influenced the presence of the following amino acids: L-anserine, asparagine, ethanolamine, gamma-aminobutyric acid, and norleucine. Asparagine was a significant predictor of a lower probability of caries experience in a logistic regression model. Conclusions: Salivary amino acids are associated with undernutrition in children, and the presence of asparagine in saliva relates to a lower caries risk.-
Descrição: dc.descriptionPostgraduate Program in Dentistry Federal University of Ceara UFC-
Descrição: dc.descriptionDepartment of Clinical Dentistry Federal University of Ceara UFC-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University, São Vicente-
Descrição: dc.descriptionUT Health School of Dentistry, 7500 Cambridge St., Suite 5306-
Descrição: dc.descriptionInstitute of Biosciences São Paulo State University, São Vicente-
Idioma: dc.languageen-
Relação: dc.relationEuropean Archives of Paediatric Dentistry-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subjectAmino Acids-
Palavras-chave: dc.subjectCaries-
Palavras-chave: dc.subjectChild Nutrition Disorders-
Palavras-chave: dc.subjectProtein Energy Malnutrition-
Palavras-chave: dc.subjectSaliva-
Título: dc.titleAssociation of asparagine in saliva with a lower risk of early childhood caries in undernourished children: a cross-sectional study-
Tipo de arquivo: dc.typelivro digital-
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