3D Filaments Based on Polyhydroxy Butyrate—Micronized Bacterial Cellulose for Tissue Engineering Applications

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Autor(es): dc.contributorUniversity of Araraquara (UNIARA)-
Autor(es): dc.contributorUniversidade de São Paulo (USP)-
Autor(es): dc.contributorBiosmart Nanotechnology LTDA-
Autor(es): dc.contributorState University of Rio de Janeiro (UEJR)-
Autor(es): dc.contributorUniversidade Federal de Uberlândia (UFU)-
Autor(es): dc.contributorUniversidade Estadual Paulista (UNESP)-
Autor(es): dc.contributorUniversidade Federal do ABC (UFABC)-
Autor(es): dc.creatorCelestino, Matheus F.-
Autor(es): dc.creatorLima, Lais R.-
Autor(es): dc.creatorFontes, Marina-
Autor(es): dc.creatorBatista, Igor T. S.-
Autor(es): dc.creatorMulinari, Daniella R.-
Autor(es): dc.creatorDametto, Alessandra-
Autor(es): dc.creatorRattes, Raphael A.-
Autor(es): dc.creatorAmaral, André C.-
Autor(es): dc.creatorAssunção, Rosana M. N.-
Autor(es): dc.creatorRibeiro, Clovis A.-
Autor(es): dc.creatorCastro, Guillermo R.-
Autor(es): dc.creatorBarud, Hernane S.-
Data de aceite: dc.date.accessioned2025-08-21T17:50:07Z-
Data de disponibilização: dc.date.available2025-08-21T17:50:07Z-
Data de envio: dc.date.issued2025-04-29-
Data de envio: dc.date.issued2023-09-01-
Fonte completa do material: dc.identifierhttp://dx.doi.org/10.3390/jfb14090464-
Fonte completa do material: dc.identifierhttps://hdl.handle.net/11449/299645-
Fonte: dc.identifier.urihttp://educapes.capes.gov.br/handle/11449/299645-
Descrição: dc.descriptionIn this work, scaffolds based on poly(hydroxybutyrate) (PHB) and micronized bacterial cellulose (BC) were produced through 3D printing. Filaments for the printing were obtained by varying the percentage of micronized BC (0.25, 0.50, 1.00, and 2.00%) inserted in relation to the PHB matrix. Despite the varying concentrations of BC, the biocomposite filaments predominantly contained PHB functional groups, as Fourier transform infrared spectroscopy (FTIR) demonstrated. Thermogravimetric analyses (i.e., TG and DTG) of the filaments showed that the peak temperature (Tpeak) of PHB degradation decreased as the concentration of BC increased, with the lowest being 248 °C, referring to the biocomposite filament PHB/2.0% BC, which has the highest concentration of BC. Although there was a variation in the thermal behavior of the filaments, it was not significant enough to make printing impossible, considering that the PHB melting temperature was 170 °C. Biological assays indicated the non-cytotoxicity of scaffolds and the provision of cell anchorage sites. The results obtained in this research open up new paths for the application of this innovation in tissue engineering.-
Descrição: dc.descriptionBiopolymers and Biomaterials Group Postgraduate Program in Biotechnology University of Araraquara (UNIARA), SP-
Descrição: dc.descriptionInstitute of Chemistry University of São Paulo (USP), SP-
Descrição: dc.descriptionBiosmart Nanotechnology LTDA, SP-
Descrição: dc.descriptionDepartment of Mechanics and Energy State University of Rio de Janeiro (UEJR), RJ-
Descrição: dc.descriptionFaculty of Integrated Sciences of Pontal (FACIP) Federal University of Uberlandia (UFU), Pontal Campus, MG-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP), SP-
Descrição: dc.descriptionNanomedicine Research Unit (Nanomed) Center for Natural and Human Sciences Federal University of ABC (UFABC), SP-
Descrição: dc.descriptionInstitute of Chemistry São Paulo State University (UNESP), SP-
Idioma: dc.languageen-
Relação: dc.relationJournal of Functional Biomaterials-
???dc.source???: dc.sourceScopus-
Palavras-chave: dc.subject3D printing-
Palavras-chave: dc.subjectmicronized bacterial cellulose-
Palavras-chave: dc.subjectpoly(hydroxybutyrate)-
Palavras-chave: dc.subjectscaffolds-
Palavras-chave: dc.subjecttissue engineering-
Título: dc.title3D Filaments Based on Polyhydroxy Butyrate—Micronized Bacterial Cellulose for Tissue Engineering Applications-
Tipo de arquivo: dc.typelivro digital-
Aparece nas coleções:Repositório Institucional - Unesp

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